The conceptualisation of obsessive-compulsive disorder (OCD) as a dysfunctional state within cortico-striato-thalamo-cortical loops is predominantly influenced by recent findings from neuroimaging, which allowed for probing brain regions, neurotransmitters and metabolites involved. Based on Part I: Concepts from pathophysiology and genetics (81) we present a selective review of findings from neuroimaging in OCD including related findings from cognitive neuroscience and neuropsychology. Among the most recent approaches are longitudinal investigations performed concomitantly to psychotherapy and pharmacotherapy, the use of parallel imaging techniques, inclusion of healthy relatives and explicit separation of OCD symptom factors, respectively.
|Translated title of the contribution||Neurobiology of obsessive-compulsive disorder: Part II: Concepts and findings from neuroimaging|
|Number of pages||8|
|Publication status||Published - 2009|
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)