Necrotizing Lymphadenitis: Kikuchi-Fujimoto disease alias lupus lymphadenitis?

J. P. Cramer, S. Schmiedel, N. G. Alegre, H. Schäfer, G. D. Burchard, H. Merz*

*Corresponding author for this work
23 Citations (Scopus)


Differentiation between lymphadenopathy in potentially life-threatening systemic lupus erythematosus (SLE) and self-limiting necrotizing lymphadenitis, also called Kikuchi- Fujimoto disease (KFD), is difficult. In the past, co-occurrence of SLE and KFD has been described repeatedly in case reports. Here, we report a case of necrotizing lymphadenitis, describe the clinical and histopathologic features in detail and discuss the current literature. KFD may in fact be a histopathologic characteristic of SLE supporting the hypothesis that KFD is a rare manifestation of SLE. To clarify whether KFD is the same entity as lupus lymphadenitis, more cases with SLE and lymphadenopathy should be examined in detail.

Original languageEnglish
Issue number1
Pages (from-to)89-92
Number of pages4
Publication statusPublished - 01.01.2010


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