Navigation of a magnetic micro-robot through a cerebral aneurysm phantom with magnetic particle imaging

Anna C. Bakenecker*, Anselm von Gladiss, Hannes Schwenke, André Behrends, Thomas Friedrich, Kerstin Lüdtke-Buzug, Alexander Neumann, Joerg Barkhausen, Franz Wegner, Thorsten M. Buzug

*Corresponding author for this work
4 Citations (Scopus)

Abstract

Cerebral aneurysms are potentially life threatening and nowadays treated by a catheter-guided coiling or by a neurosurgical clipping intervention. Here, we propose a helically shaped magnetic micro-robot, which can be steered by magnetic fields in an untethered manner and could be applied for a novel coiling procedure. This is shown by navigating the micro-robot through an additively manufactured phantom of a human cerebral aneurysm. The magnetic fields are applied with a magnetic particle imaging (MPI) scanner, which allows for the navigation and tomographic visualization by the same machine. With MPI the actuation process can be visualized with a localization accuracy of 0.68 mm and an angiogram can be acquired both without any radiation exposure. First in-vitro phantom experiments are presented, showing an idea of a robot conducted treatment of cerebral aneurysms.

Original languageEnglish
Article number14082
JournalScientific Reports
Volume11
Issue number1
ISSN2045-2322
DOIs
Publication statusPublished - 12.2021

Research Areas and Centers

  • Academic Focus: Biomedical Engineering

DFG Research Classification Scheme

  • 205-32 Medical Physics, Biomedical Engineering
  • 205-30 Radiology, Nuclear Medicine, Radiation Therapy and Radiobiology

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