Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012

Roger Dumke; Christiane Schnee; Mathias W. Pletz; Jan Rupp; Enno Jacobs; Konrad Sachse; Gernot Rohde; M. Dreher; C. Cornelissen; W. Knüppel; I. Armari; D. Stolz; N. Suttorp; H. Schütte; P. Creutz; T. Bauer; T. Weiß; W. Pankow; A. Lies; D. Thiemig; B. Hauptmeier; D. Wehde; M. Suermann; S. Ewig; M. Prediger; G. Zernia; G. Höffken; M. Kolditz; T. Welte; G. Barten; M. Abrahamczik; J. Naim; W. Kröner; T. Illig; N. Klopp; C. Kroegel; M. Pletz; M. Pletz; S. Schütz; R. Hörster; G. Rohde; H. Buschmann; R. Kröning; T. Schaberg; I. Hering; C. Schumann; T. Illmann; the CAPNETZ Study Group; M. Wallner

doi:10.3201/eid2103.140927

Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012

Roger Dumke, Christiane Schnee, Mathias W. Pletz, Jan Rupp, Enno Jacobs, Konrad Sachse, Gernot Rohde, M. Dreher, C. Cornelissen, W. Knüppel, I. Armari, D. Stolz, N. Suttorp, H. Schütte, P. Creutz, T. Bauer, T. Weiß, W. Pankow, A. Lies, D. ThiemigB. Hauptmeier, D. Wehde, M. Suermann, S. Ewig, M. Prediger, G. Zernia, G. Höffken, M. Kolditz, T. Welte, G. Barten, M. Abrahamczik, J. Naim, W. Kröner, T. Illig, N. Klopp, C. Kroegel, M. Pletz, M. Pletz, S. Schütz, R. Hörster, G. Rohde, H. Buschmann, R. Kröning, T. Schaberg, I. Hering, C. Schumann, T. Illmann, the CAPNETZ Study Group, M. Wallner

38 Citations (Scopus)

Abstract

Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are diffcult to propagate, and can cause clinically indistinguish able disease patterns. During 2011-2012, we used molecu lar methods to test adult patients in Germany with confrmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and lev els of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peakforthese infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring condi tions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemi- ology of these pathogens in CAP.

Original language	English
Journal	Emerging Infectious Diseases
Volume	21
Issue number	3
Pages (from-to)	426-434
Number of pages	9
ISSN	1080-6040
DOIs	https://doi.org/10.3201/eid2103.140927
Publication status	Published - 01.01.2015

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

DFG Research Classification Scheme

2.21-03 Medical Microbiology and Mycology, Hygiene, Molecular Infection Biology
2.21-05 Immunology
2.22-13 Pneumology, Thoracic Surgery
2.22-02 Public Health, Healthcare Research, Social and Occupational Medicine
2.22-31 Clinical Infectiology and Tropical Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Dumke, R., Schnee, C., Pletz, M. W., Rupp, J., Jacobs, E., Sachse, K., Rohde, G., Dreher, M., Cornelissen, C., Knüppel, W., Armari, I., Stolz, D., Suttorp, N., Schütte, H., Creutz, P., Bauer, T., Weiß, T., Pankow, W., Lies, A., ... Wallner, M. (2015). Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012. Emerging Infectious Diseases, 21(3), 426-434. https://doi.org/10.3201/eid2103.140927

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title = "Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012",

abstract = "Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are diffcult to propagate, and can cause clinically indistinguish able disease patterns. During 2011-2012, we used molecu lar methods to test adult patients in Germany with confrmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and lev els of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peakforthese infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring condi tions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemi- ology of these pathogens in CAP.",

author = "Roger Dumke and Christiane Schnee and Pletz, {Mathias W.} and Jan Rupp and Enno Jacobs and Konrad Sachse and Gernot Rohde and M. Dreher and C. Cornelissen and W. Kn{\"u}ppel and I. Armari and D. Stolz and N. Suttorp and H. Sch{\"u}tte and P. Creutz and T. Bauer and T. Wei{\ss} and W. Pankow and A. Lies and D. Thiemig and B. Hauptmeier and D. Wehde and M. Suermann and S. Ewig and M. Prediger and G. Zernia and G. H{\"o}ffken and M. Kolditz and T. Welte and G. Barten and M. Abrahamczik and J. Naim and W. Kr{\"o}ner and T. Illig and N. Klopp and C. Kroegel and M. Pletz and M. Pletz and S. Sch{\"u}tz and R. H{\"o}rster and G. Rohde and H. Buschmann and R. Kr{\"o}ning and T. Schaberg and I. Hering and C. Schumann and T. Illmann and {the CAPNETZ Study Group} and M. Wallner",

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doi = "10.3201/eid2103.140927",

language = "English",

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Dumke, R, Schnee, C, Pletz, MW, Rupp, J, Jacobs, E, Sachse, K, Rohde, G, Dreher, M, Cornelissen, C, Knüppel, W, Armari, I, Stolz, D, Suttorp, N, Schütte, H, Creutz, P, Bauer, T, Weiß, T, Pankow, W, Lies, A, Thiemig, D, Hauptmeier, B, Wehde, D, Suermann, M, Ewig, S, Prediger, M, Zernia, G, Höffken, G, Kolditz, M, Welte, T, Barten, G, Abrahamczik, M, Naim, J, Kröner, W, Illig, T, Klopp, N, Kroegel, C, Pletz, M , Pletz, M, Schütz, S, Hörster, R, Rohde, G, Buschmann, H, Kröning, R, Schaberg, T, Hering, I, Schumann, C, Illmann, T, the CAPNETZ Study Group & Wallner, M 2015, 'Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012', Emerging Infectious Diseases, vol. 21, no. 3, pp. 426-434. https://doi.org/10.3201/eid2103.140927

TY - JOUR

T1 - Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012

AU - Dumke, Roger

AU - Schnee, Christiane

AU - Pletz, Mathias W.

AU - Rupp, Jan

AU - Jacobs, Enno

AU - Sachse, Konrad

AU - Rohde, Gernot

AU - Dreher, M.

AU - Cornelissen, C.

AU - Knüppel, W.

AU - Armari, I.

AU - Stolz, D.

AU - Suttorp, N.

AU - Schütte, H.

AU - Creutz, P.

AU - Bauer, T.

AU - Weiß, T.

AU - Pankow, W.

AU - Lies, A.

AU - Thiemig, D.

AU - Hauptmeier, B.

AU - Wehde, D.

AU - Suermann, M.

AU - Ewig, S.

AU - Prediger, M.

AU - Zernia, G.

AU - Höffken, G.

AU - Kolditz, M.

AU - Welte, T.

AU - Barten, G.

AU - Abrahamczik, M.

AU - Naim, J.

AU - Kröner, W.

AU - Illig, T.

AU - Klopp, N.

AU - Kroegel, C.

AU - Pletz, M.

AU - Schütz, S.

AU - Hörster, R.

AU - Rohde, G.

AU - Buschmann, H.

AU - Kröning, R.

AU - Schaberg, T.

AU - Hering, I.

AU - Schumann, C.

AU - Illmann, T.

AU - the CAPNETZ Study Group

AU - Wallner, M.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are diffcult to propagate, and can cause clinically indistinguish able disease patterns. During 2011-2012, we used molecu lar methods to test adult patients in Germany with confrmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and lev els of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peakforthese infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring condi tions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemi- ology of these pathogens in CAP.

AB - Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are diffcult to propagate, and can cause clinically indistinguish able disease patterns. During 2011-2012, we used molecu lar methods to test adult patients in Germany with confrmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and lev els of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peakforthese infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring condi tions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemi- ology of these pathogens in CAP.

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U2 - 10.3201/eid2103.140927

DO - 10.3201/eid2103.140927

M3 - Journal articles

C2 - 25693633

AN - SCOPUS:84928651076

SN - 1080-6040

VL - 21

SP - 426

EP - 434

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 3

ER -

Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012

Abstract

Research Areas and Centers

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UN SDGs

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