Mycoplasma pneumoniae and chlamydia spp. Infection in community-acquired pneumonia, Germany, 2011–2012

Roger Dumke, Christiane Schnee, Mathias W. Pletz, Jan Rupp, Enno Jacobs, Konrad Sachse, Gernot Rohde, M. Dreher, C. Cornelissen, W. Knüppel, I. Armari, D. Stolz, N. Suttorp, H. Schütte, P. Creutz, T. Bauer, T. Weiß, W. Pankow, A. Lies, D. ThiemigB. Hauptmeier, D. Wehde, M. Suermann, S. Ewig, M. Prediger, G. Zernia, G. Höffken, M. Kolditz, T. Welte, G. Barten, M. Abrahamczik, J. Naim, W. Kröner, T. Illig, N. Klopp, C. Kroegel, M. Pletz, M. Pletz, S. Schütz, R. Hörster, G. Rohde, H. Buschmann, R. Kröning, T. Schaberg, I. Hering, C. Schumann, T. Illmann, the CAPNETZ Study Group, M. Wallner

38 Citations (Scopus)


Mycoplasma pneumoniae and Chlamydia spp., which are associated with community-acquired pneumonia (CAP), are diffcult to propagate, and can cause clinically indistinguish able disease patterns. During 2011-2012, we used molecu lar methods to test adult patients in Germany with confrmed CAP for infection with these 2 pathogens. Overall, 12.3% (96/783) of samples were positive for M. pneumoniae and 3.9% (31/794) were positive for Chlamydia spp.; C. psittaci (2.1%) was detected more frequently than C. pneumoniae (1.4%). M. pneumoniae P1 type 1 predominated, and lev els of macrolide resistance were low (3.1%). Quarterly rates of M. pneumoniae-positive samples ranged from 1.5% to 27.3%, showing a strong epidemic peakforthese infections, but of Chlamydia spp. detection was consistent throughout the year. M. pneumoniae-positive patients were younger and more frequently female, had fewer co-occurring condi tions, and experienced milder disease than did patients who tested negative. Clinicians should be aware of the epidemi- ology of these pathogens in CAP.

Original languageEnglish
JournalEmerging Infectious Diseases
Issue number3
Pages (from-to)426-434
Number of pages9
Publication statusPublished - 01.01.2015

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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