Background and purpose: Colorectal cancer is one of the most common malignant diseases in the Western world. Multiple prognostic factors have already been identified, but the influence of multiple carcinomas on patient outcome has not yet been sufficiently assessed. We have analysed if the presence of a second or multiple tumours changes the long-term survival in patients with colorectal cancer. Patients and methods: In our institution (University Hospital Luebeck, Germany), a total of 1,500 patients with colorectal cancer were operated on between 1992 and 2005; 6 patients (19%) had multiple tumours. These patients were divided into groups according to the time of presentation of the second tumour and statistically analysed. Only curatively operated patients were included to minimise concomitant prognostic factors. Results: There were no significant differences in survival in the various groups. Further, the long-term outcome in patients with solitary tumours did not differ significantly from those with multiple tumours. Conclusion: The presence of multiple tumours in patients with colorectal cancer is not an independent prognostic factor for their long-term survival. Therefore multiple tumours are not associated with a worse outcome and these patients warrant curative treatment and adequate follow-up.
|Translated title of the contribution
|Multiple carcinomas: Prognostic factor in patients with colorectal cancer?
|Number of pages
|Published - 01.12.2010