Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

Maria Sabater-Lleal, Jie Huang, Daniel Chasman, Silvia Naitza, Abbas Dehghan, Andrew D. Johnson, Alexander Teumer, Alex P. Reiner, Lasse Folkersen, Saonli Basu, Alicja R. Rudnicka, Stella Trompet, Anders Mälarstig, Jens Baumert, Joshua C. Bis, Xiuqing Guo, Jouke J. Hottenga, So Youn Shin, Lorna M. Lopez, Jari LahtiToshiko Tanaka, Lisa R. Yanek, Tiphaine Oudot-Mellakh, James F. Wilson, Pau Navarro, Jennifer E. Huffman, Tatijana Zemunik, Susan Redline, Reena Mehra, Drazen Pulanic, Igor Rudan, Alan F. Wright, Ivana Kolcic, Ozren Polasek, Sarah H. Wild, Harry Campbell, J. David Curb, Robert Wallace, Simin Liu, Charles B. Eaton, Diane M. Becker, Lewis C. Becker, Stefania Bandinelli, Katri Räikkönen, Elisabeth Widen, Aarno Palotie, Myriam Fornage, David Green, Myron Gross, Gail Davies, Sarah E. Harris, David C. Liewald, John M. Starr, Frances M.K. Williams, Peter J. Grant, Timothy D. Spector, Rona J. Strawbridge, Angela Silveira, Bengt Sennblad, Fernando Rivadeneira, Andre G. Uitterlinden, Oscar H. Franco, Albert Hofman, Jenny Van Dongen, Gonneke Willemsen, Dorret I. Boomsma, Jie Yao, Nancy Swords Jenny, Talin Haritunians, Barbara McKnight, Thomas Lumley, Kent D. Taylor, Jerome I. Rotter, Bruce M. Psaty, Annette Peters, Christian Gieger, Thomas Illig, Anne Grotevendt, Georg Homuth, Henry Völzke, Thomas Kocher, Anuj Goel, Maria Grazia Franzosi, Udo Seedorf, Robert Clarke, Maristella Steri, Kirill V. Tarasov, Serena Sanna, David Schlessinger, David J. Stott, Naveed Sattar, Brendan M. Buckley, Ann Rumley, Gordon D. Lowe, Wendy L. McArdle, Ming Huei Chen, Geoffrey H. Tofler, Jaejoon Song, Eric Boerwinkle, Aaron R. Folsom, Lynda M. Rose, Anders Franco-Cereceda, Martina Teichert, M. Arfan Ikram, Thomas H. Mosley, Steve Bevan, Martin Dichgans, Peter M. Rothwell, Cathie L.M. Sudlow, Jemma C. Hopewell, John C. Chambers, Danish Saleheen, Jaspal S. Kooner, John Danesh, Christopher P. Nelson, Jeanette Erdmann, Muredach P. Reilly, Sekar Kathiresan, Heribert Schunkert, Pierre Emmanuel Morange, Luigi Ferrucci, Johan G. Eriksson, David Jacobs, Ian J. Deary, Nicole Soranzo, Jacqueline C.M. Witteman, Eco J.C. De Geus, Russell P. Tracy, Caroline Hayward, Wolfgang Koenig, Francesco Cucca, J. Wouter Jukema, Per Eriksson, Sudha Seshadri, Hugh S. Markus, Hugh Watkins, Nilesh J. Samani, Henri Wallaschofski, Nicholas L. Smith, David Tregouet, Paul M. Ridker, Weihong Tang, David P. Strachan, Anders Hamsten^*, Christopher J. O'DonnellShow 125 moreShow less