MRI of the liver: Can true FISP replace HASTE?

Christoph U. Herborn*, Florian Vogt, Thomas C. Lauenstein, Mathias Goyen, Jörg F. Debatin, Stephan G. Ruehm

*Corresponding author for this work
33 Citations (Scopus)


Purpose: To determine the diagnostic accuracy of two fast breath-hold magnetic resonance (MR) imaging sequences, half-Fourier acquired single turbo spin-echo (HASTE) and true fast imaging with steady state precession (TrueFISP), for the detection and characterization of focal liver lesions. Materials and Methods: A total of 186 patients with suspected focal liver lesions were enrolled in this study. All patients underwent the same standardized study protocol including HASTE and TrueFISP. A consensus reading based on all available image data served as a standard of reference for classifying lesions into cysts, hemangiomas, focal nodular hyperplasia, or malignant/other lesions. All malignant lesions, as well as hepatic adenomas and abscesses, were histologically verified. Each separated by an eight-week interval, HASTE and TrueFISP images were retrespectively reviewed in random order for the detection and characterization of focal hepatic lesions. Finally, a receiver operating characteristic (ROC) analysis was calculated. Results: HASTE images had an overall sensitivity of 0.86 and a specificity of 0.91, whereas TrueFISP showed an overall sensitivity and specificity of 0.79 and 0.83, respectively (p>0.1). Conclusion: Neither HASTE nor TrueFISP alone are sufficient for the detection and characterization of hepatic lesions.

Original languageEnglish
JournalJournal of Magnetic Resonance Imaging
Issue number2
Pages (from-to)190-196
Number of pages7
Publication statusPublished - 01.02.2003


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