Motorized capsule for shadow-free OCT imaging and synchronous beam control

Antonio López-Marín; Geert Springeling; Robert Beurskens; Heleen van Beusekom; Antonius F.W. van der Steen; Arjun D. Koch; Brett E. Bouma; Robert Huber; Gijs V.A.N. Soest; Tianshi Wang

doi:10.1364/OL.44.003641

Motorized capsule for shadow-free OCT imaging and synchronous beam control

Antonio López-Marín, Geert Springeling, Robert Beurskens, Heleen van Beusekom, Antonius F.W. van der Steen, Arjun D. Koch, Brett E. Bouma, Robert Huber, Gijs V.A.N. Soest, Tianshi Wang^*

^*Corresponding author for this work

Institute of Biomedical Optics

3 Citations (Scopus)

Abstract

We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments using the capsule. The results show that the capsule can potentially be a useful tool for diagnostic OCT imaging and OCT-guided biopsy and therapy of the esophagus.

Original language	English
Journal	Optics Letters
Volume	44
Issue number	15
Pages (from-to)	3641-3644
Number of pages	4
ISSN	0146-9592
DOIs	https://doi.org/10.1364/OL.44.003641
Publication status	Published - 01.08.2019

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Academic Focus: Biomedical Engineering

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10.1364/OL.44.003641

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@article{3070a60156eb4789a22c9dff909d1bb9,

title = "Motorized capsule for shadow-free OCT imaging and synchronous beam control",

abstract = "We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments using the capsule. The results show that the capsule can potentially be a useful tool for diagnostic OCT imaging and OCT-guided biopsy and therapy of the esophagus.",

author = "Antonio L{\'o}pez-Mar{\'i}n and Geert Springeling and Robert Beurskens and {van Beusekom}, Heleen and {van der Steen}, {Antonius F.W.} and Koch, {Arjun D.} and Bouma, {Brett E.} and Robert Huber and Soest, {Gijs V.A.N.} and Tianshi Wang",

note = "Funding Information: Funding. Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) (Veni-15940, ZonMW 104003006); Deutsche Forschungsgemeinschaft (DFG) (DFG-EXC 2167); H2020 European Research Council (ERC) (ERC CoG_ ENCOMOLE-2i, 646669). Publisher Copyright: {\textcopyright} 2019 Optical Society of America. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.",

year = "2019",

month = aug,

day = "1",

doi = "10.1364/OL.44.003641",

language = "English",

volume = "44",

pages = "3641--3644",

journal = "Optics Letters",

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TY - JOUR

T1 - Motorized capsule for shadow-free OCT imaging and synchronous beam control

AU - López-Marín, Antonio

AU - Springeling, Geert

AU - Beurskens, Robert

AU - van Beusekom, Heleen

AU - van der Steen, Antonius F.W.

AU - Koch, Arjun D.

AU - Bouma, Brett E.

AU - Huber, Robert

AU - Soest, Gijs V.A.N.

AU - Wang, Tianshi

N1 - Funding Information: Funding. Nederlandse Organisatie voor Wetenschappelijk Onderzoek (NWO) (Veni-15940, ZonMW 104003006); Deutsche Forschungsgemeinschaft (DFG) (DFG-EXC 2167); H2020 European Research Council (ERC) (ERC CoG_ ENCOMOLE-2i, 646669). Publisher Copyright: © 2019 Optical Society of America. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.

PY - 2019/8/1

Y1 - 2019/8/1

N2 - We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments using the capsule. The results show that the capsule can potentially be a useful tool for diagnostic OCT imaging and OCT-guided biopsy and therapy of the esophagus.

AB - We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments using the capsule. The results show that the capsule can potentially be a useful tool for diagnostic OCT imaging and OCT-guided biopsy and therapy of the esophagus.

UR - http://www.scopus.com/inward/record.url?scp=85070899148&partnerID=8YFLogxK

U2 - 10.1364/OL.44.003641

DO - 10.1364/OL.44.003641

M3 - Journal articles

C2 - 31368932

AN - SCOPUS:85070899148

SN - 0146-9592

VL - 44

SP - 3641

EP - 3644

JO - Optics Letters

JF - Optics Letters

IS - 15

ER -

Motorized capsule for shadow-free OCT imaging and synchronous beam control

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