Model-Based Detection of White Matter in Optical Coherence Tomography Data

Femando Gasea, Lukas Ramrath

Abstract

A method for white matter detection in Optical Coherence Tomography A-Scans is presented. The Kaiman filter is used to obtain a slope change estimate of the intensity signal. The estimate is subsequently analyzed by a spike detection algorithm and then evaluated by a neural network binary classifier (Perceptron). The capability of the proposed method is shown through the quantitative evaluation of simulated A-Scans. The method was also applied to data obtained from a rat's brain in vitro. Results show that the developed algorithm identifies less false positives than other two spike detection methods, thus, enhancing the robustness and quality of detection.

Original languageEnglish
Title of host publication2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Number of pages4
PublisherIEEE
Publication date01.12.2007
Pages1623-1626
Article number4352617
ISBN (Print)978-1-4244-0787-3, 978-1-4244-0788-0
DOIs
Publication statusPublished - 01.12.2007
Event29th Annual International Conference of IEEE-EMBS, Engineering in Medicine and Biology Society - Lyon, France
Duration: 23.08.200726.08.2007
Conference number: 70818

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