Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia - Diagnostic Value of Pulse Oximetry

Sebastian Brandt; Oliver Kimberger; Benjamin Weber; Anne Klose; Swetlana Stockmann; Wilfried Schmeller; Hartmut Gehring; Patrick Kellner

doi:10.52547/wjps.11.1.111

Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia - Diagnostic Value of Pulse Oximetry

Sebastian Brandt, Oliver Kimberger, Benjamin Weber, Anne Klose, Swetlana Stockmann, Wilfried Schmeller, Hartmut Gehring, Patrick Kellner

Abstract

BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels.

METHODS: In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7® in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011.

RESULTS: In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry.

CONCLUSION: Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia.

Original language	English
Journal	World journal of plastic surgery
Volume	11
Issue number	1
Pages (from-to)	111-116
Number of pages	6
ISSN	2228-7914
DOIs	https://doi.org/10.52547/wjps.11.1.111
Publication status	Published - 2022

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10.52547/wjps.11.1.111

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@article{3acf8ed0dc924ddf91b297f5ddae9089,

title = "Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia - Diagnostic Value of Pulse Oximetry",

abstract = "BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7{\textregistered}) can measure methemoglobin levels.METHODS: In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7{\textregistered} in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011.RESULTS: In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry.CONCLUSION: Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia.",

author = "Sebastian Brandt and Oliver Kimberger and Benjamin Weber and Anne Klose and Swetlana Stockmann and Wilfried Schmeller and Hartmut Gehring and Patrick Kellner",

year = "2022",

doi = "10.52547/wjps.11.1.111",

language = "English",

volume = "11",

pages = "111--116",

journal = "World journal of plastic surgery",

issn = "2228-7914",

number = "1",

}

TY - JOUR

T1 - Methaemoglobinemia after Liposuction under Tumescent Local Anaesthesia - Diagnostic Value of Pulse Oximetry

AU - Brandt, Sebastian

AU - Kimberger, Oliver

AU - Weber, Benjamin

AU - Klose, Anne

AU - Stockmann, Swetlana

AU - Schmeller, Wilfried

AU - Gehring, Hartmut

AU - Kellner, Patrick

PY - 2022

Y1 - 2022

N2 - BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels.METHODS: In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7® in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011.RESULTS: In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry.CONCLUSION: Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia.

AB - BACKGROUND: Tumescent local anaesthesia with prilocain can lead to clinically significant methemoglobin levels. New generation multiple wavelength pulse oximeters (e. g. Masimo Radical 7®) can measure methemoglobin levels.METHODS: In this prospective observational study we compared the venous methemoglobin levels and the corresponding pulse oximetric values of the Radical 7® in patients undergoing tumescent local anaesthesia for liposuction procedures. The measurements were performed in Hanseklinik, Luebeck, Germany between 2008 and 2011.RESULTS: In 133 patients, we measured a maximum methemoglobin level of 18 per cent. In a Bland-Altman analysis we found a mean bias of +2.2 % (-4.1 to 8.4 limits of agreement) for pulse oximetric values compared to hemoximetry.CONCLUSION: Pulse oximetric measurement of methemoglobin is an early-warning tool for the detection of clinically significant methaemoglobinemia in patients with tumescent local anaesthesia.

U2 - 10.52547/wjps.11.1.111

DO - 10.52547/wjps.11.1.111

M3 - Journal articles

C2 - 35592237

SN - 2228-7914

VL - 11

SP - 111

EP - 116

JO - World journal of plastic surgery

JF - World journal of plastic surgery

IS - 1

ER -