Metabolomics Biomarkers for Breast Cancer

Ulrich L. Günther*

*Corresponding author for this work
39 Citations (Scopus)

Abstract

Metabolomics represents a more recent addition to the range of omics tools, which are increasingly used in clinical applications. By measuring the composition of small molecules in tissues, blood or urine, it provides a sensitive molecular readout often associated with disease and its states, especially in cancer. Changes in metabolism related to cancer are increasingly well understood and are seen as a major hallmark of cancer. This review covers metabolomics used in human breast cancers, with a focus on its application in clinical diagnostics. There are clear indications that metabolomics could be a useful addition to currently established clinical diagnostic tools for breast cancer, including the possibility to detect cancer and to predict treatment responses and survival rates from blood and tissue samples.

Original languageEnglish
JournalPathobiology
Volume82
Issue number3-4
Pages (from-to)153-165
Number of pages13
ISSN1015-2008
DOIs
Publication statusPublished - 23.09.2015

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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