Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

Tianshi Wang; Tom Pfeiffer; Joost Daemen; Frits Mastik; Wolfgang Wieser; A. F.W. Van Der Steen; Robert Huber; Gijs Van Soest

doi:10.1117/12.2506151

Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

Tianshi Wang^*, Tom Pfeiffer, Joost Daemen, Frits Mastik, Wolfgang Wieser, A. F.W. Van Der Steen, Robert Huber, Gijs Van Soest

^*Corresponding author for this work

Institute of Biomedical Optics

Abstract

We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

Original language	English
Title of host publication	Diagnostic and Therapeutic Applications of Light in Cardiology 2019
Editors	Kenton W. Gregory , Laura Marcu
Number of pages	5
Volume	10855
Publisher	SPIE
Publication date	26.02.2019
Article number	1085503
DOIs	https://doi.org/10.1117/12.2506151
Publication status	Published - 26.02.2019
Event	Diagnostic and Therapeutic Applications of Light in Cardiology 2019 - San Francisco, United States Duration: 02.02.2019 → 03.02.2019 Conference number: 148274

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Academic Focus: Biomedical Engineering

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Wang, T., Pfeiffer, T., Daemen, J., Mastik, F., Wieser, W., Van Der Steen, A. F. W., Huber, R., & Van Soest, G. (2019). Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. In K. W. Gregory , & L. Marcu (Eds.), Diagnostic and Therapeutic Applications of Light in Cardiology 2019 (Vol. 10855). Article 1085503 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10855). SPIE. https://doi.org/10.1117/12.2506151

Wang, Tianshi ; Pfeiffer, Tom ; Daemen, Joost et al. / Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. Diagnostic and Therapeutic Applications of Light in Cardiology 2019. editor / Kenton W. Gregory ; Laura Marcu. Vol. 10855 SPIE, 2019. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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title = "Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging",

abstract = "We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.",

author = "Tianshi Wang and Tom Pfeiffer and Joost Daemen and Frits Mastik and Wolfgang Wieser and \{Van Der Steen\}, \{A. F.W.\} and Robert Huber and \{Van Soest\}, Gijs",

note = "Publisher Copyright: {\textcopyright} 2019 SPIE. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.; Diagnostic and Therapeutic Applications of Light in Cardiology 2019 ; Conference date: 02-02-2019 Through 03-02-2019",

year = "2019",

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series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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Wang, T, Pfeiffer, T, Daemen, J, Mastik, F, Wieser, W, Van Der Steen, AFW, Huber, R & Van Soest, G 2019, Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. in K W. Gregory & L Marcu (eds), Diagnostic and Therapeutic Applications of Light in Cardiology 2019. vol. 10855, 1085503, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10855, SPIE, Diagnostic and Therapeutic Applications of Light in Cardiology 2019, San Francisco, California, United States, 02.02.19. https://doi.org/10.1117/12.2506151

Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. / Wang, Tianshi; Pfeiffer, Tom; Daemen, Joost et al.
Diagnostic and Therapeutic Applications of Light in Cardiology 2019. ed. / Kenton W. Gregory ; Laura Marcu. Vol. 10855 SPIE, 2019. 1085503 (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10855).

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

AU - Wang, Tianshi

AU - Pfeiffer, Tom

AU - Daemen, Joost

AU - Mastik, Frits

AU - Wieser, Wolfgang

AU - Van Der Steen, A. F.W.

AU - Huber, Robert

AU - Van Soest, Gijs

N1 - Conference code: 148274

PY - 2019/2/26

Y1 - 2019/2/26

N2 - We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

AB - We demonstrate megahertz intravascular Doppler Optical Coherence Tomography (OCT). The OCT system relies on a 1.1 mm diameter motorized catheter and a 1.5 MHz Fourier Domain Mode Locked (FDML) laser. By resolving the phase shift between adjoint A-lines, the flow pattern image can be reconstructed. Imaging experiments were carried out in swine coronary artery in vitro at a speed of 600 frames/s. The MHz sweep rate not only allows us to investigate flow velocity of up to 37.5 cm/s without phase-unwrapping, but also enables dynamic flow imaging at high frame rate.

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U2 - 10.1117/12.2506151

DO - 10.1117/12.2506151

M3 - Conference contribution

VL - 10855

T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

BT - Diagnostic and Therapeutic Applications of Light in Cardiology 2019

A2 - W. Gregory , Kenton

A2 - Marcu, Laura

PB - SPIE

T2 - Diagnostic and Therapeutic Applications of Light in Cardiology 2019

Y2 - 2 February 2019 through 3 February 2019

ER -

Wang T, Pfeiffer T, Daemen J, Mastik F, Wieser W, Van Der Steen AFW et al. Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging. In W. Gregory K, Marcu L, editors, Diagnostic and Therapeutic Applications of Light in Cardiology 2019. Vol. 10855. SPIE. 2019. 1085503. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.2506151

Megahertz intravascular Doppler optical coherence tomography enables simultaneous morphological and flow pattern imaging

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