Medikamentöse Myomtherapie

Translated title of the contribution: Drug therapy of uterine fibroids

Michael K. Bohlmann*, A. Hornemann, N. Sänger, A. Hackethal, K. von Horn, P. S. Wilkens, F. Hoellen

*Corresponding author for this work


Background: Uterine fibroids affect a large number of women in the reproductive years. Treatment: Therapeutic options of symptomatic fibroids include surgical, radiological interventional and conservative approaches with drugs. Medicinal approaches are mainly used to control bleeding, in cases of contraindications to surgical or radiological treatment and preoperatively to improve the initial situation. Due to the hormone-responsive growth of uterine fibroids, gonadotropin-releasing hormone (GnRH) analogs played a major role in the treatment, whereas combined oral contraceptives, progestogens and intrauterine systems that release hormones were administered in an off-label setting. In 2012 ulipristal acetate, a selective progesterone receptor modulator, was approved by the European Medicines Agency to be used in women with symptomatic fibroids. Aim: This review article illustrates the advantages and disadvantages of the individual drug treatment options.

Translated title of the contributionDrug therapy of uterine fibroids
Original languageGerman
JournalGynakologische Endokrinologie
Issue number4
Pages (from-to)226-231
Number of pages6
Publication statusPublished - 01.10.2015


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