Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues

Alfred Vogel; Joachim Noack; Gereon Hüttmann; Günther Paltauf

doi:10.1088/1742-6596/59/1/053

Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues

Alfred Vogel^*, Joachim Noack, Gereon Hüttmann, Günther Paltauf

^*Corresponding author for this work

Institute of Biomedical Optics

Karl-Franzens-University Graz

16 Citations (Scopus)

Abstract

We investigated the working mechanisms of femtosecond laser nanoprocessing in biomaterials with oscillator pulses of 80 MHz repetition rate and with amplified pulses of 1 kHz repetition rate. Plasma formation in water, the evolution of the temperature distribution, thermoelastic stress generation, and stress-induced cavitation bubble formation were numerically simulated for NA 1.3 and the outcome compared to experimental results. A comparison of the thresholds for the various physical effects with experimental parameters enables to assess the working mechanisms of both modalities for cell surgery.

Original language	English
Article number	053
Journal	Journal of Physics: Conference Series
Volume	59
Issue number	1
Pages (from-to)	249-254
Number of pages	6
ISSN	1742-6588
DOIs	https://doi.org/10.1088/1742-6596/59/1/053
Publication status	Published - 01.04.2007

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Academic Focus: Biomedical Engineering

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Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues

Abstract

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