Mechanisms of femtosecond laser nanoprocessing of biological cells and tissues

Alfred Vogel*, Joachim Noack, Gereon Hüttmann, Günther Paltauf

*Corresponding author for this work
16 Citations (Scopus)


We investigated the working mechanisms of femtosecond laser nanoprocessing in biomaterials with oscillator pulses of 80 MHz repetition rate and with amplified pulses of 1 kHz repetition rate. Plasma formation in water, the evolution of the temperature distribution, thermoelastic stress generation, and stress-induced cavitation bubble formation were numerically simulated for NA 1.3 and the outcome compared to experimental results. A comparison of the thresholds for the various physical effects with experimental parameters enables to assess the working mechanisms of both modalities for cell surgery.

Original languageEnglish
Article number053
JournalJournal of Physics: Conference Series
Issue number1
Pages (from-to)249-254
Number of pages6
Publication statusPublished - 01.04.2007

Research Areas and Centers

  • Academic Focus: Biomedical Engineering


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