MBECS: Microbiome Batch Effects Correction Suite

Michael Olbrich; Axel Künstner; Hauke Busch

doi:10.1186/s12859-023-05252-w

MBECS: Microbiome Batch Effects Correction Suite

Michael Olbrich^*, Axel Künstner, Hauke Busch^*

^*Corresponding author for this work

Institute of Experimental Dermatology

6 Citations (Scopus)

Abstract

Despite the availability of batch effect correcting algorithms (BECA), no comprehensive tool that combines batch correction and evaluation of the results exists for microbiome datasets. This work outlines the Microbiome Batch Effects Correction Suite development that integrates several BECAs and evaluation metrics into a software package for the statistical computation framework R.

Original language	English
Article number	1
Journal	BMC Bioinformatics
Volume	24
Issue number	1
Pages (from-to)	182
Number of pages	1
ISSN	1367-4803
DOIs	https://doi.org/10.1186/s12859-023-05252-w
Publication status	Published - 03.05.2023

Funding

Open Access funding enabled and organized by Projekt DEAL. Hauke Busch acknowledges funding by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under Germany`s Excellence Strategy (EXC 2167-390884018).

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

DFG Research Classification Scheme

2.21-05 Immunology
2.22-19 Dermatology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1186/s12859-023-05252-w

Cite this

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title = "MBECS: Microbiome Batch Effects Correction Suite",

abstract = "Despite the availability of batch effect correcting algorithms (BECA), no comprehensive tool that combines batch correction and evaluation of the results exists for microbiome datasets. This work outlines the Microbiome Batch Effects Correction Suite development that integrates several BECAs and evaluation metrics into a software package for the statistical computation framework R.",

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T2 - Microbiome Batch Effects Correction Suite

AU - Olbrich, Michael

AU - Künstner, Axel

AU - Busch, Hauke

PY - 2023/5/3

Y1 - 2023/5/3

N2 - Despite the availability of batch effect correcting algorithms (BECA), no comprehensive tool that combines batch correction and evaluation of the results exists for microbiome datasets. This work outlines the Microbiome Batch Effects Correction Suite development that integrates several BECAs and evaluation metrics into a software package for the statistical computation framework R.

AB - Despite the availability of batch effect correcting algorithms (BECA), no comprehensive tool that combines batch correction and evaluation of the results exists for microbiome datasets. This work outlines the Microbiome Batch Effects Correction Suite development that integrates several BECAs and evaluation metrics into a software package for the statistical computation framework R.

UR - https://www.scopus.com/pages/publications/85158042636

UR - https://www.mendeley.com/catalogue/11ac7147-0ab7-38b4-b3d0-047d830e8b1d/

U2 - 10.1186/s12859-023-05252-w

DO - 10.1186/s12859-023-05252-w

M3 - Journal articles

C2 - 37138207

AN - SCOPUS:85158042636

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JF - BMC Bioinformatics

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MBECS: Microbiome Batch Effects Correction Suite

Abstract

Funding

Research Areas and Centers

DFG Research Classification Scheme

UN SDGs

Access to Document

Other files and links

Fingerprint

EXC 2167: Precision Medicine in Chronic Inflammation (PMI)

Cite this

MBECS: Microbiome Batch Effects Correction Suite

Abstract

Funding

Research Areas and Centers

DFG Research Classification Scheme

UN SDGs

Access to Document

Other files and links

Fingerprint

Projects

EXC 2167: Precision Medicine in Chronic Inflammation (PMI)

Cite this