Obese individuals share behavioral characteristics with drug/alcohol addicts as well as obsessive compulsive disease. Deep brain stimulation (DBS) has been used successfully in these disorders, thus warranting an evaluation in obesity. A woman with treatment-resistant depression as well as severe obesity was selected for DBS of the nucleus accumbens (NAcc) bilaterally with depression being the primary and obesity being the secondary target of treatment. Compared to earlier bariatric surgery, the patient showed accelerated weight loss after DBS. Also, depression was significantly reduced. The current case suggests that DBS of the NAcc warrants further evaluation in patients unresponsive to other treatments.

Original languageEnglish
JournalNeurocase : case studies in neuropsychology, neuropsychiatry, and behavioural neurology
Issue number1
Pages (from-to)49-53
Number of pages5
Publication statusPublished - 02.2018


Dive into the research topics of 'Massive weight loss following deep brain stimulation of the nucleus accumbens in a depressed woman'. Together they form a unique fingerprint.

Cite this