Massive creatine kinase elevations with quetiapine: Report of two cases - A case report

J. P. Klein; U. Fiedler; H. Appel; A. Quante; Maria C. Jockers-Scherübl

doi:10.1055/s-2006-931478

Massive creatine kinase elevations with quetiapine: Report of two cases - A case report

J. P. Klein, U. Fiedler, H. Appel, A. Quante, Maria C. Jockers-Scherübl^*

^*Corresponding author for this work

Clinic of Psychiatry and Psychotherapy

Charite - Universitatsmedizin Berlin

16 Citations (Scopus)

Abstract

Massive elevations of serum creatine kinase (CK) can occur in a significant number of patients treated with neuroleptics in the absence of neuroleptic malignant syndrome (NMS). We report two cases of CK-elevations associated with quetiapine treatment, which disappeared after drug discontinuation. To our knowledge, case number one is the first case of quetiapine-induced CK elevation in a neuroleptic-naïve patient. We thus suggest CK assessment when myalgia occurs with neuroleptic treatment.

Original language	English
Journal	Pharmacopsychiatry
Volume	39
Issue number	1
Pages (from-to)	39-40
Number of pages	2
ISSN	0176-3679
DOIs	https://doi.org/10.1055/s-2006-931478
Publication status	Published - 01.2006

Research Areas and Centers

Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1055/s-2006-931478

Cite this

@article{4d3d728be4a04fe2894a3bbccc95bb0c,

title = "Massive creatine kinase elevations with quetiapine: Report of two cases - A case report",

abstract = "Massive elevations of serum creatine kinase (CK) can occur in a significant number of patients treated with neuroleptics in the absence of neuroleptic malignant syndrome (NMS). We report two cases of CK-elevations associated with quetiapine treatment, which disappeared after drug discontinuation. To our knowledge, case number one is the first case of quetiapine-induced CK elevation in a neuroleptic-na{\"i}ve patient. We thus suggest CK assessment when myalgia occurs with neuroleptic treatment.",

author = "Klein, \{J. P.\} and U. Fiedler and H. Appel and A. Quante and Jockers-Scher{\"u}bl, \{Maria C.\}",

year = "2006",

month = jan,

doi = "10.1055/s-2006-931478",

language = "English",

volume = "39",

pages = "39--40",

journal = "Pharmacopsychiatry",

issn = "0176-3679",

publisher = "Georg Thieme Verlag",

number = "1",

}

TY - JOUR

T1 - Massive creatine kinase elevations with quetiapine: Report of two cases - A case report

AU - Klein, J. P.

AU - Fiedler, U.

AU - Appel, H.

AU - Quante, A.

AU - Jockers-Scherübl, Maria C.

PY - 2006/1

Y1 - 2006/1

N2 - Massive elevations of serum creatine kinase (CK) can occur in a significant number of patients treated with neuroleptics in the absence of neuroleptic malignant syndrome (NMS). We report two cases of CK-elevations associated with quetiapine treatment, which disappeared after drug discontinuation. To our knowledge, case number one is the first case of quetiapine-induced CK elevation in a neuroleptic-naïve patient. We thus suggest CK assessment when myalgia occurs with neuroleptic treatment.

AB - Massive elevations of serum creatine kinase (CK) can occur in a significant number of patients treated with neuroleptics in the absence of neuroleptic malignant syndrome (NMS). We report two cases of CK-elevations associated with quetiapine treatment, which disappeared after drug discontinuation. To our knowledge, case number one is the first case of quetiapine-induced CK elevation in a neuroleptic-naïve patient. We thus suggest CK assessment when myalgia occurs with neuroleptic treatment.

UR - https://www.scopus.com/pages/publications/32544432754

U2 - 10.1055/s-2006-931478

DO - 10.1055/s-2006-931478

M3 - Journal articles

C2 - 16453254

AN - SCOPUS:32544432754

SN - 0176-3679

VL - 39

SP - 39

EP - 40

JO - Pharmacopsychiatry

JF - Pharmacopsychiatry

IS - 1

ER -

Massive creatine kinase elevations with quetiapine: Report of two cases - A case report

Abstract

Research Areas and Centers

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this