Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Hendrik P.N. Scholl; Andreas M. Schuster; Reinhard Vonthein; Eberhart Zrenner

doi:10.1016/S0042-6989(02)00034-2

Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Hendrik P.N. Scholl^*, Andreas M. Schuster, Reinhard Vonthein, Eberhart Zrenner

^*Corresponding author for this work

Institute of Medical Biometry and Statistic

25 Citations (Scopus)

Abstract

In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

Original language	English
Journal	Vision Research
Volume	42
Issue number	8
Pages (from-to)	1053-1061
Number of pages	9
ISSN	0042-6989
DOIs	https://doi.org/10.1016/S0042-6989(02)00034-2
Publication status	Published - 2002

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10.1016/S0042-6989(02)00034-2

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abstract = "In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.",

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AB - In order to evaluate the function of the retina in Best macular dystrophy (BMD) 18 patients were examined by means of the multifocal electroretinogram (mfERG). The mfERG peak amplitudes of the central and pericentral responses were significantly reduced in the BMD patients (p<0.001). The ERG amplitude decrease of the central response was significantly correlated with visual acuity loss and with the funduscopic staging. The implicit times in more eccentric groups were slightly but significantly increased. The markedly reduced mfERG amplitudes with only slightly increased implicit times may indicate cone photoreceptor cell loss or damage to the cone outer segments.

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Mapping of retinal function in Best macular dystrophy using multifocal electroretinography

Abstract

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