Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

Franz Wegner; Thomas Friedrich; Anselm von Gladiss; Ulrike Grzyska; Malte M. Sieren; Kerstin Lüdtke-Buzug; Alex Frydrychowicz; Thorsten M. Buzug; Jörg Barkhausen; Julian Haegele

doi:10.1007/s00270-019-02347-x

Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

Franz Wegner^*, Thomas Friedrich, Anselm von Gladiss, Ulrike Grzyska, Malte M. Sieren, Kerstin Lüdtke-Buzug, Alex Frydrychowicz, Thorsten M. Buzug, Jörg Barkhausen, Julian Haegele

^*Corresponding author for this work

17 Citations (Scopus)

Abstract

Purpose: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). Materials and Methods: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3–4 mm; length: 11–38 mm) and materials (stainless steel, platinum–chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. Results: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. Conclusion: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.

Original language	English
Journal	CardioVascular and Interventional Radiology
Volume	43
Issue number	2
Pages (from-to)	331-338
Number of pages	8
ISSN	0174-1551
DOIs	https://doi.org/10.1007/s00270-019-02347-x
Publication status	Published - 01.02.2020

Funding

This study partially was funded by Federal Ministry of Education and Research BMBF Grant Nos. 13GW0071D, 13GW0069A, 13GW0230B, and 01DL17010A.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 9 Industry, Innovation, and Infrastructure

Research Areas and Centers

Academic Focus: Biomedical Engineering

DFG Research Classification Scheme

2.22-30 Radiology
2.22-32 Medical Physics, Biomedical Technology

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Cite this

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title = "Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study",

abstract = "Purpose: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). Materials and Methods: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3–4 mm; length: 11–38 mm) and materials (stainless steel, platinum–chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. Results: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. Conclusion: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.",

author = "Franz Wegner and Thomas Friedrich and \{von Gladiss\}, Anselm and Ulrike Grzyska and Sieren, \{Malte M.\} and Kerstin L{\"u}dtke-Buzug and Alex Frydrychowicz and Buzug, \{Thorsten M.\} and J{\"o}rg Barkhausen and Julian Haegele",

note = "Funding Information: This study partially was funded by Federal Ministry of Education and Research BMBF Grant Nos. 13GW0071D, 13GW0069A, 13GW0230B, and 01DL17010A. Publisher Copyright: {\textcopyright} 2019, Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.",

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doi = "10.1007/s00270-019-02347-x",

language = "English",

volume = "43",

pages = "331--338",

journal = "CardioVascular and Interventional Radiology",

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T1 - Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

AU - Wegner, Franz

AU - Friedrich, Thomas

AU - von Gladiss, Anselm

AU - Grzyska, Ulrike

AU - Sieren, Malte M.

AU - Lüdtke-Buzug, Kerstin

AU - Frydrychowicz, Alex

AU - Buzug, Thorsten M.

AU - Barkhausen, Jörg

AU - Haegele, Julian

N1 - Funding Information: This study partially was funded by Federal Ministry of Education and Research BMBF Grant Nos. 13GW0071D, 13GW0069A, 13GW0230B, and 01DL17010A. Publisher Copyright: © 2019, Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.

PY - 2020/2/1

Y1 - 2020/2/1

N2 - Purpose: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). Materials and Methods: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3–4 mm; length: 11–38 mm) and materials (stainless steel, platinum–chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. Results: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. Conclusion: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.

AB - Purpose: To illustrate the potential of magnetic particle imaging (MPI) for stent lumen imaging in comparison with clinical computed tomography (CT) and magnetic resonance imaging (MRI). Materials and Methods: Imaging of eight tracer-filled, stented vessel phantoms and a tracer-filled, non-stented reference phantom for each diameter was performed on a preclinical MPI scanner: eight commercially available coronary stents of different dimensions (diameter: 3–4 mm; length: 11–38 mm) and materials (stainless steel, platinum–chromium) were implanted into silicone vessel phantoms. For comparison, all vessel phantoms were also visualized by MRI and CT. Two radiologists assessed the images regarding stent-induced artifacts using a 5-point grading scale. Results: The visualization of all stented vessel phantoms was achieved without stent-induced artifacts with MPI. In contrast, MRI and CT images revealed multiform stent-induced artifacts. Conclusion: Given its clinical introduction, MPI has the potential to overcome the disadvantages of MRI and CT concerning the visualization of the stent lumen.

UR - https://www.scopus.com/pages/publications/85073926413

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JO - CardioVascular and Interventional Radiology

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ER -

Magnetic Particle Imaging: Artifact-Free Metallic Stent Lumen Imaging in a Phantom Study

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