Lymphoepithelioma-like carcinoma and simultaneous marginal zone lymphoma of the skin: A case report

Niklas Gebauer*, Hartmut Merz, Karl W. Ottmann, Michael Tronnier

*Corresponding author for this work
2 Citations (Scopus)

Abstract

Lymphoepithelioma-like carcinoma (LELC) of the skin is a rare malignant epithelial neoplasm, which shows histological resemblance of nasopharyngeal carcinoma (Schmincke-Regaud tumor). Similar tumors have been reported at a variety of sites, including salivary gland, tonsil, thymus, stomach, and uterus. Extracutaneous LELC shows frequently an association with Epstein-Barr virus, whereas Epstein-Barr virus in LELC of the skin has been described only once till now. LELC of the skin usually presents as a papulonodular lesion on the head or neck of patients above 50 years of age. Here, we describe a collision tumor with an LELC and a marginal zone lymphoma of the skin in a 75-year-old female patient. To our knowledge, this is the first reported case of an association between these 2 malignancies, and the possibility of a causal relationship is discussed.

Original languageEnglish
JournalAmerican Journal of Dermatopathology
Volume36
Issue number2
ISSN0193-1091
DOIs
Publication statusPublished - 01.02.2014

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