TY - JOUR
T1 - Lost in transition: Biomarkers of remodeling in patients with asthma
AU - Bahmer, Thomas
AU - Bülow Sand, Jannie Marie
AU - Weckmann, Markus
N1 - Publisher Copyright:
Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.
Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - The term 'remodeling' is often referred to via biomarkers that reflect the endstage of a process, although it rather reflects a continuous process starting in childhood and progressing to all age-levels in patients with asthma. Hence, only few biomarkers or surrogates are able to 'capture' its spatiotemporal component, and hardly any are ready for routine use in clinical practice. Given the clinical impact of the remodeling processes, new biomarkers are needed to adequately treat patients with asthma and objectively monitor treatment response beyond symptom control and lung function.
AB - The term 'remodeling' is often referred to via biomarkers that reflect the endstage of a process, although it rather reflects a continuous process starting in childhood and progressing to all age-levels in patients with asthma. Hence, only few biomarkers or surrogates are able to 'capture' its spatiotemporal component, and hardly any are ready for routine use in clinical practice. Given the clinical impact of the remodeling processes, new biomarkers are needed to adequately treat patients with asthma and objectively monitor treatment response beyond symptom control and lung function.
UR - http://www.scopus.com/inward/record.url?scp=85075961404&partnerID=8YFLogxK
U2 - 10.1097/MCP.0000000000000641
DO - 10.1097/MCP.0000000000000641
M3 - Scientific review articles
C2 - 31652154
AN - SCOPUS:85075961404
SN - 1070-5287
VL - 26
SP - 40
EP - 46
JO - Current Opinion in Pulmonary Medicine
JF - Current Opinion in Pulmonary Medicine
IS - 1
ER -
