Long-Term Follow-Up of Children, Adolescents, and Young Adult Cancer Survivors

Inken Hilgendorf*, Corinna Bergelt, Carsten Bokemeyer, Peter Kaatsch, Ulf Seifart, Alexander Stein, Thorsten Langer

*Corresponding author for this work


Background and Summary: Thanks to increasing cure rates to currently >80%, children, adolescents, and young adults (CAYA) survive their cancer much more frequently today than decades ago. Due to their long life expectancy, CAYA cancer survivors are at a particular risk of long-term sequelae from the cancer itself or the therapy applied; this requires specific follow-up, and preventative or even therapeutic interventions. Thus, compared to the normal population, morbidity and mortality may be significantly increased. In 2 of 3 survivors, the cancer and the respective treatment can lead to late effects, even after 30 years, which require specific therapy; in about one-third of these cases, these effects are classed as severe. Applying structured follow-up could identify these late effects at an early stage and initiate immediate treatment. In 2018, a working group dealing with long-term survival after cancer detected <40 years of age was founded within the framework of the National Cancer Plan of the German Federal Ministry of Health.

Original languageEnglish
JournalOncology Research and Treatment
Issue number4
Pages (from-to)184-189
Number of pages6
Publication statusPublished - 03.2021

Research Areas and Centers

  • Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)


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