TY - JOUR
T1 - Long-Term Effects of an Intensive Prevention Program After Acute Myocardial Infarction
AU - Osteresch, Rico
AU - Fach, Andreas
AU - Frielitz, Fabian Simon
AU - Meyer, Sven
AU - Schmucker, Johannes
AU - Rühle, Stephan
AU - Retzlaff, Tina
AU - Hadwiger, Moritz
AU - Härle, Tobias
AU - Elsässer, Albrecht
AU - Katalinic, Alexander
AU - Eitel, Ingo
AU - Hambrecht, Rainer
AU - Wienbergen, Harm
N1 - Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2021/9/1
Y1 - 2021/9/1
N2 - Effective long-term prevention after myocardial infarction (MI) is crucial to reduce recurrent events. In this study the effects of a 12-months intensive prevention program (IPP), based on repetitive contacts between non-physician “prevention assistants” and patients, were evaluated. Patients after MI were randomly assigned to the IPP versus usual care (UC). Effects of IPP on risk factor control, clinical events and costs were investigated after 24 months. In a substudy efficacy of short reinterventions after more than 24 months (“Prevention Boosts”) was analyzed. IPP was associated with a significantly better risk factor control compared to UC after 24 months and a trend towards less serious clinical events (12.5% vs 20.9%, log-rank p = 0.06). Economic analyses revealed that already after 24 months cost savings due to event reduction outweighted the costs of the prevention program (costs per patient 1,070 € in IPP vs 1,170 € in UC). Short reinterventions (“Prevention Boosts”) more than 24 months after MI further improved risk factor control, such as LDL cholesterol and blood pressure lowering. In conclusion, IPP was associated with numerous beneficial effects on risk factor control, clinical events and costs. The study thereby demonstrates the efficacy of preventive long-term concepts after MI, based on repetitive contacts between non-physician coworkers and patients.
AB - Effective long-term prevention after myocardial infarction (MI) is crucial to reduce recurrent events. In this study the effects of a 12-months intensive prevention program (IPP), based on repetitive contacts between non-physician “prevention assistants” and patients, were evaluated. Patients after MI were randomly assigned to the IPP versus usual care (UC). Effects of IPP on risk factor control, clinical events and costs were investigated after 24 months. In a substudy efficacy of short reinterventions after more than 24 months (“Prevention Boosts”) was analyzed. IPP was associated with a significantly better risk factor control compared to UC after 24 months and a trend towards less serious clinical events (12.5% vs 20.9%, log-rank p = 0.06). Economic analyses revealed that already after 24 months cost savings due to event reduction outweighted the costs of the prevention program (costs per patient 1,070 € in IPP vs 1,170 € in UC). Short reinterventions (“Prevention Boosts”) more than 24 months after MI further improved risk factor control, such as LDL cholesterol and blood pressure lowering. In conclusion, IPP was associated with numerous beneficial effects on risk factor control, clinical events and costs. The study thereby demonstrates the efficacy of preventive long-term concepts after MI, based on repetitive contacts between non-physician coworkers and patients.
UR - http://www.scopus.com/inward/record.url?scp=85111578039&partnerID=8YFLogxK
U2 - 10.1016/j.amjcard.2021.05.034
DO - 10.1016/j.amjcard.2021.05.034
M3 - Journal articles
C2 - 34238446
AN - SCOPUS:85111578039
VL - 154
SP - 7
EP - 13
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
ER -