Long-Term Effects of an Intensive Prevention Program After Acute Myocardial Infarction

Rico Osteresch, Andreas Fach, Fabian Simon Frielitz, Sven Meyer, Johannes Schmucker, Stephan Rühle, Tina Retzlaff, Moritz Hadwiger, Tobias Härle, Albrecht Elsässer, Alexander Katalinic, Ingo Eitel, Rainer Hambrecht, Harm Wienbergen*

*Corresponding author for this work
1 Citation (Scopus)

Abstract

Effective long-term prevention after myocardial infarction (MI) is crucial to reduce recurrent events. In this study the effects of a 12-months intensive prevention program (IPP), based on repetitive contacts between non-physician “prevention assistants” and patients, were evaluated. Patients after MI were randomly assigned to the IPP versus usual care (UC). Effects of IPP on risk factor control, clinical events and costs were investigated after 24 months. In a substudy efficacy of short reinterventions after more than 24 months (“Prevention Boosts”) was analyzed. IPP was associated with a significantly better risk factor control compared to UC after 24 months and a trend towards less serious clinical events (12.5% vs 20.9%, log-rank p = 0.06). Economic analyses revealed that already after 24 months cost savings due to event reduction outweighted the costs of the prevention program (costs per patient 1,070 € in IPP vs 1,170 € in UC). Short reinterventions (“Prevention Boosts”) more than 24 months after MI further improved risk factor control, such as LDL cholesterol and blood pressure lowering. In conclusion, IPP was associated with numerous beneficial effects on risk factor control, clinical events and costs. The study thereby demonstrates the efficacy of preventive long-term concepts after MI, based on repetitive contacts between non-physician coworkers and patients.

Original languageEnglish
JournalAmerican Journal of Cardiology
Volume154
Pages (from-to)7-13
Number of pages7
ISSN0002-9149
DOIs
Publication statusPublished - 01.09.2021

Research Areas and Centers

  • Research Area: Center for Population Medicine and Public Health (ZBV)
  • Centers: Cardiological Center Luebeck (UHZL)

DFG Research Classification Scheme

  • 205-12 Cardiology, Angiology

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