Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31

Torbjoern G. Nygaard, Deborah Raymond, Caiping Chen, Ichizo Nishino, Paul E. Greene, Danna Jennings, Gary A. Heiman, Christine Klein, Rachel J. Saunders-Pullman, Patricia Kramer, Laurie J. Ozelius, Susan B. Bressman*

*Corresponding author for this work
89 Citations (Scopus)


Essential myoclonus-dystonia is a neurological condition characterized by myoclonic and dystonic muscle contractions and the absence of other neurological signs or laboratory abnormalities; it is often responsive to alcohol. The disorder may be familial with apparent autosomal dominant inheritance. We report a large kindred with essential familial myoclonus- dystonia and map a locus for the disorder to a 28-cM region of chromosome 7q21-q31.

Original languageEnglish
JournalAnnals of Neurology
Issue number5
Pages (from-to)794-798
Number of pages5
Publication statusPublished - 17.11.1999


Dive into the research topics of 'Localization of a gene for myoclonus-dystonia to chromosome 7q21-q31'. Together they form a unique fingerprint.

Cite this