TY - JOUR
T1 - Lipopolysaccharide-induced in vivo activation of follicular dendritic cells is tumor necrosis factor receptor-1 independent
AU - Milićević, Novica M.
AU - Milićević, Živana
AU - Westermann, Jurgen A.
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 2012/1
Y1 - 2012/1
N2 - It is well recognized that tumor necrosis factor receptor-1 (TNFR1) signaling pathway (with lymphotoxin-β receptor) is of critical importance for the development, activation, and clustering of follicular dendritic cells (FDCs) within the lymphoid follicles. However, further information on the molecular control of these processes is very sparse. Here, we show that intravenous application of lipopolysaccharide induces the clear and prominent morphological signs of FDC development and activation in vivo, which is independent of TNFR1 pathway.
AB - It is well recognized that tumor necrosis factor receptor-1 (TNFR1) signaling pathway (with lymphotoxin-β receptor) is of critical importance for the development, activation, and clustering of follicular dendritic cells (FDCs) within the lymphoid follicles. However, further information on the molecular control of these processes is very sparse. Here, we show that intravenous application of lipopolysaccharide induces the clear and prominent morphological signs of FDC development and activation in vivo, which is independent of TNFR1 pathway.
UR - http://www.scopus.com/inward/record.url?scp=83655201333&partnerID=8YFLogxK
U2 - 10.1002/ar.21466
DO - 10.1002/ar.21466
M3 - Journal articles
C2 - 21957083
AN - SCOPUS:83655201333
SN - 1932-8486
VL - 295
SP - 87
EP - 90
JO - Anatomical Record
JF - Anatomical Record
IS - 1
ER -
