TY - JOUR
T1 - Lifetime-comorbidity of obsessive-compulsive disorder and subclinical obsessive-compulsive disorder in northern Germany
AU - Grabe, Hans Joergen
AU - Meyer, Christian
AU - Hapke, Ulfert
AU - Rumpf, Hans Juergen
AU - Freyberger, Harald Juergen
AU - Dilling, Horst
AU - John, Ulrich
N1 - Funding Information:
■ Acknowledgments This study is part of the German research network“Analytical Epidemiology of Substance Abuse (ANEPSA)”. Factors related to the use and abuse of psychoactive substances are analyzed by different research groups in the context of several longitudinal studies. Contact persons are Dr. Büringer/Dr. Küfner (IFT Institute for Therapy Research, Munich), Prof. Dr. Wittchen (Max-Planck Institute, Munich) and Prof. Dr. John (University of Greifswald)/Prof. Dr. Dilling (Medical University of Lübeck). The research network is funded in the context of the program “Biological and psycho-social factors of drug abuse and dependence”by the Federal Ministry of Education, Science, Research, and Technology.
Copyright:
Copyright 2007 Elsevier B.V., All rights reserved.
PY - 2001
Y1 - 2001
N2 - Objective: Inspite of the worldwide relevance of obsessive-compulsive disorder (OCD), there is a substantial lack of data on comorbidity in OCD and subclinical OCD in the general population. Methods: German versions of the DSM-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 4075 persons aged 18-64 years, living in a northern German region. Results In both genders, high rates of comorbid depressive disorders were found in OCD and subclinical OCD, whereas somatoform pain disorder was only associated with OCD. In female subjects, OCD was additionally associated with social and specific phobias, alcohol, nicotine and sedative dependence, PTSD and atypical eating disorder. Conclusion Due to low comorbidity rates, subclinical OCD seems to represent an independent syndrome not restricted to the presence of other axis-I diagnoses. Comorbidity patterns show a disposition to anxiety and to depressive disorders in OCD and subclinical OCD. A broad association with obsessive-compulsive spectrum disorders could not be confirmed in our general population sample.
AB - Objective: Inspite of the worldwide relevance of obsessive-compulsive disorder (OCD), there is a substantial lack of data on comorbidity in OCD and subclinical OCD in the general population. Methods: German versions of the DSM-IV adapted Composite International Diagnostic Interview were administered to a representative sample of 4075 persons aged 18-64 years, living in a northern German region. Results In both genders, high rates of comorbid depressive disorders were found in OCD and subclinical OCD, whereas somatoform pain disorder was only associated with OCD. In female subjects, OCD was additionally associated with social and specific phobias, alcohol, nicotine and sedative dependence, PTSD and atypical eating disorder. Conclusion Due to low comorbidity rates, subclinical OCD seems to represent an independent syndrome not restricted to the presence of other axis-I diagnoses. Comorbidity patterns show a disposition to anxiety and to depressive disorders in OCD and subclinical OCD. A broad association with obsessive-compulsive spectrum disorders could not be confirmed in our general population sample.
UR - http://www.scopus.com/inward/record.url?scp=0034792730&partnerID=8YFLogxK
U2 - 10.1007/s004060170047
DO - 10.1007/s004060170047
M3 - Journal articles
C2 - 11697574
AN - SCOPUS:0034792730
SN - 0940-1334
VL - 251
SP - 130
EP - 135
JO - European Archives of Psychiatry and Clinical Neuroscience
JF - European Archives of Psychiatry and Clinical Neuroscience
IS - 3
ER -
