Life-threatening pemphigus vulgaris

Nina Schumacher, Sophie Charlotte Mook, Iakov Shimanovich, Detlef Zillikens, Enno Schmidt*

*Corresponding author for this work


A 69-year-old male was transferred to our department by helicopter on a Sunday morning from the intensive care burn unit of another university hospital. In this unit, he had been treated for 3 days including a radical debridement of unattached skin. Before, he had been admitted in a dermatology department of another university hospital for exacerbated pemphigus vulgaris. Pemphigus had been diagnosed 2 years ago and treated with tapering doses of initially high-dose oral corticosteroids and mycophenolate mofetil before dramatic worsening of oral and skin lesions 3 months ago with a weight loss of 25 kg and generalized erosions and blistering. At the time of presentation in our clinic due to his poor general condition his only immunosuppressive medication was mycophenolate mofetil at a dose of 1 g/day.

Original languageEnglish
Title of host publicationClinical Cases in Autoimmune Blistering Diseases
Number of pages9
PublisherSpringer International Publishing
Publication date01.01.2015
ISBN (Print)9783319101477
ISBN (Electronic)9783319101484
Publication statusPublished - 01.01.2015

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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