Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

György Görög; Tamás Laskay; G. Petrányi

doi:10.1016/0165-2478(85)90151-8

Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

György Görög^*, Tamás Laskay, G. Petrányi

^*Corresponding author for this work

Clinic of Infectious Diseases and Microbiology

National Institute of Haematology and Blood Transfusion Budapest

3 Citations (Scopus)

Abstract

Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

Original language	English
Journal	Immunology Letters
Volume	11
Issue number	2
Pages (from-to)	107-109
Number of pages	3
ISSN	0165-2478
DOIs	https://doi.org/10.1016/0165-2478(85)90151-8
Publication status	Published - 01.01.1985

Research Areas and Centers

Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0165-2478(85)90151-8

Cite this

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title = "Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor",

abstract = "Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.",

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T1 - Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

AU - Görög, György

AU - Laskay, Tamás

AU - Petrányi, G.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

AB - Investigating the functional effects of anti-T cell monoclonal antibodies (obtained through the Second International Workshop on Human Leucocyte Differentiation Antigens), antibodies to the sheep red cell receptor (CD2) were found to block lectin-dependent cytotoxicity. Blocking was seen with all anti-CD2 reagents tested regardless of epitope specificity, immunoglobulin subclass or other factors. Antibodies to other T cell differentiation antigens had no effect.

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Lectin-dependent cellular cytotoxicity by human lymphocytes is blocked by monoclonal antibodies to the sheep red cell receptor

Abstract

Research Areas and Centers

UN SDGs

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