Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR

Ralf Brinkmann*, Norbert Koop, Katharina Kamm, Gerd Geerling, Jürgen Kampmeier, Reginald Birngruber

*Corresponding author for this work


Laser thermokeratoplasty (LTK) has been performed with a continuously emitting, tunable laser diode at 1.86 μm. A study on enucleated porcine eyes was conducted in order to demonstrate the feasibility of this laser source for LTK and to determine the useful irradiation modalities. Refractive changes achieved with different application systems and a standard coagulation pattern, consisting of 8 coagulation spots on a 6 mm ring, were measured. The most promising sets of parameters were carried out in a first animal study with mini pigs. Initial refractive changes up to 6 D could be achieved in vitro and in vivo with laser powers between 120 mW and 200 mW and irradiation times of several seconds. In conclusion, the mid-IR laser diode operated at a wavelength of 1.86 μm seems to be the optimal source for a clinical LTK system.

Original languageEnglish
JournalProceedings of SPIE - The International Society for Optical Engineering
Pages (from-to)66-74
Number of pages9
Publication statusPublished - 05.12.1996
EventLasers in Ophthalmology IV - Vienna, Austria
Duration: 09.09.199609.09.1996
Conference number: 74681

Research Areas and Centers

  • Academic Focus: Biomedical Engineering


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