Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR

Ralf Brinkmann; Norbert Koop; Katharina Kamm; Gerd Geerling; Jürgen Kampmeier; Reginald Birngruber

doi:10.1117/12.260876

Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR

Ralf Brinkmann^*, Norbert Koop, Katharina Kamm, Gerd Geerling, Jürgen Kampmeier, Reginald Birngruber

^*Corresponding author for this work

Abstract

Laser thermokeratoplasty (LTK) has been performed with a continuously emitting, tunable laser diode at 1.86 μm. A study on enucleated porcine eyes was conducted in order to demonstrate the feasibility of this laser source for LTK and to determine the useful irradiation modalities. Refractive changes achieved with different application systems and a standard coagulation pattern, consisting of 8 coagulation spots on a 6 mm ring, were measured. The most promising sets of parameters were carried out in a first animal study with mini pigs. Initial refractive changes up to 6 D could be achieved in vitro and in vivo with laser powers between 120 mW and 200 mW and irradiation times of several seconds. In conclusion, the mid-IR laser diode operated at a wavelength of 1.86 μm seems to be the optimal source for a clinical LTK system.

Original language	English
Journal	Proceedings of SPIE - The International Society for Optical Engineering
Volume	2930
Pages (from-to)	66-74
Number of pages	9
ISSN	0277-786X
DOIs	https://doi.org/10.1117/12.260876
Publication status	Published - 05.12.1996
Event	Lasers in Ophthalmology IV - Vienna, Austria Duration: 09.09.1996 → 09.09.1996 Conference number: 74681

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Academic Focus: Biomedical Engineering

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10.1117/12.260876

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title = "Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR",

abstract = "Laser thermokeratoplasty (LTK) has been performed with a continuously emitting, tunable laser diode at 1.86 μm. A study on enucleated porcine eyes was conducted in order to demonstrate the feasibility of this laser source for LTK and to determine the useful irradiation modalities. Refractive changes achieved with different application systems and a standard coagulation pattern, consisting of 8 coagulation spots on a 6 mm ring, were measured. The most promising sets of parameters were carried out in a first animal study with mini pigs. Initial refractive changes up to 6 D could be achieved in vitro and in vivo with laser powers between 120 mW and 200 mW and irradiation times of several seconds. In conclusion, the mid-IR laser diode operated at a wavelength of 1.86 μm seems to be the optimal source for a clinical LTK system.",

author = "Ralf Brinkmann and Norbert Koop and Katharina Kamm and Gerd Geerling and J{\"u}rgen Kampmeier and Reginald Birngruber",

year = "1996",

month = dec,

day = "5",

doi = "10.1117/12.260876",

language = "English",

volume = "2930",

pages = "66--74",

journal = "Proceedings of SPIE - The International Society for Optical Engineering",

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TY - JOUR

T1 - Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR

AU - Brinkmann, Ralf

AU - Koop, Norbert

AU - Kamm, Katharina

AU - Geerling, Gerd

AU - Kampmeier, Jürgen

AU - Birngruber, Reginald

N1 - Conference code: 74681

PY - 1996/12/5

Y1 - 1996/12/5

N2 - Laser thermokeratoplasty (LTK) has been performed with a continuously emitting, tunable laser diode at 1.86 μm. A study on enucleated porcine eyes was conducted in order to demonstrate the feasibility of this laser source for LTK and to determine the useful irradiation modalities. Refractive changes achieved with different application systems and a standard coagulation pattern, consisting of 8 coagulation spots on a 6 mm ring, were measured. The most promising sets of parameters were carried out in a first animal study with mini pigs. Initial refractive changes up to 6 D could be achieved in vitro and in vivo with laser powers between 120 mW and 200 mW and irradiation times of several seconds. In conclusion, the mid-IR laser diode operated at a wavelength of 1.86 μm seems to be the optimal source for a clinical LTK system.

AB - Laser thermokeratoplasty (LTK) has been performed with a continuously emitting, tunable laser diode at 1.86 μm. A study on enucleated porcine eyes was conducted in order to demonstrate the feasibility of this laser source for LTK and to determine the useful irradiation modalities. Refractive changes achieved with different application systems and a standard coagulation pattern, consisting of 8 coagulation spots on a 6 mm ring, were measured. The most promising sets of parameters were carried out in a first animal study with mini pigs. Initial refractive changes up to 6 D could be achieved in vitro and in vivo with laser powers between 120 mW and 200 mW and irradiation times of several seconds. In conclusion, the mid-IR laser diode operated at a wavelength of 1.86 μm seems to be the optimal source for a clinical LTK system.

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U2 - 10.1117/12.260876

DO - 10.1117/12.260876

M3 - Conference Articles in Journals

SN - 0277-786X

VL - 2930

SP - 66

EP - 74

JO - Proceedings of SPIE - The International Society for Optical Engineering

JF - Proceedings of SPIE - The International Society for Optical Engineering

T2 - Lasers in Ophthalmology IV

Y2 - 9 September 1996 through 9 September 1996

ER -

Laser thermokeratoplasty by means of a continuously emitting laser diode in the mid-IR

Abstract

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