Kritische Extremitätenischämie bei systemischer Sklerose

Translated title of the contribution: Critical limb ischemia in systemic sclerosis

M. O. Becker*, G. Riemekasten

*Corresponding author for this work


Vascular complications are common in systemic sclerosis (SSc). Critical limb ischemia leading to gangrene or amputation occurs in more than 10% of these patients and hence is a common emergency. This report highlights the different pathogenetic mechanisms leading to critical ischemic events and provides guidance for the diagnosis and therapy. Apart from SSc-associated vasculopathy and peripheral arterial disease, thromboembolic events and rarely also vasculitis may cause critical limb ischemia. An interdisciplinary approach to the diagnosis and therapy of these lesions is mandatory. Therapy goals are the prevention of further ischemia and, if possible, revascularization as well as optimal pain management.

Translated title of the contributionCritical limb ischemia in systemic sclerosis
Original languageGerman
JournalZeitschrift fur Rheumatologie
Issue number4
Pages (from-to)261-269
Number of pages9
Publication statusPublished - 06.2012

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


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