Kongenitale gerinnungsstörungen: Gynäkologische und neonatologische aspekte

Congenital pathologies of the coagulation cascade are of great importance during pregnancy and birth due to the potential effects on both mother and fetus. Furthermore, gynecologists are faced with special challenges in cases of coagulation diseases in adolescence. This interdisciplinary review will focus on the possible impact of congenital coagulation disorders in three specific phases: the neonatal period, female adolescence and pregnancy. It is the aim of the manuscript to assess an algorithm which guides from symptoms to diagnosis and to present the most important hereditary abnormalities of coagulation. The diseases are divided into those with an increased tendency to coagulation (thrombophilia) and those with an increased risk of bleeding (hemophilia). Acquired bleeding disorders will not be described in detail.