Non-clathrin-coated vesicles mediate membrane traffic through the Golgi complex. The proteins that constitute the coats of these vesicles have similar molecular weights to the clathrin coat proteins. A major component of the coat of non-clathrin-coated vesicles, β-COP, has significant homology with the clathrin coat protein β-adaptin, indicating that the coats of the two different classes of vesicles may be structurally and functionally homologous.
Research Areas and Centers
- Academic Focus: Center for Infection and Inflammation Research (ZIEL)