Investigating dOCT signal origins and bringing a new contrast to fluorescence imaging

Noah Heldt; Martin Ahrens; Mario Pieper; Robert Schönherr; Lucie Jeschke; Peter König; Marko Lampe; Gereon Hüttmann

doi:10.1364/ECBO.2025.S4B.1

Investigating dOCT signal origins and bringing a new contrast to fluorescence imaging

Noah Heldt^*
, Martin Ahrens
, Mario Pieper
, Robert Schönherr
, Lucie Jeschke
, Peter König
, Marko Lampe (Shared Last Author)
, Gereon Hüttmann (Shared Last Author)

^*Corresponding author for this work

Abstract

We investigated the dynamic optical coherence tomography (dOCT) signal origins by correlative measurements together with spinning disk confocal microscopy (SDM). Furthermore, we propose dynamic contrasting for detecting organelle movement signatures in the sub-second range.

Original language	English
Title of host publication	European Conferences on Biomedical Optics 2025
Publisher	Optica Publishing Group
Publication date	2025
Pages	S4B.1
DOIs	https://doi.org/10.1364/ECBO.2025.S4B.1
Publication status	Published - 2025

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10.1364/ECBO.2025.S4B.1

Cite this

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title = "Investigating dOCT signal origins and bringing a new contrast to fluorescence imaging",

abstract = "We investigated the dynamic optical coherence tomography (dOCT) signal origins by correlative measurements together with spinning disk confocal microscopy (SDM). Furthermore, we propose dynamic contrasting for detecting organelle movement signatures in the sub-second range.",

author = "Noah Heldt and Martin Ahrens and Mario Pieper and Robert Sch{\"o}nherr and Lucie Jeschke and Peter K{\"o}nig and Marko Lampe and Gereon H{\"u}ttmann",

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doi = "10.1364/ECBO.2025.S4B.1",

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T1 - Investigating dOCT signal origins and bringing a new contrast to fluorescence imaging

AU - Heldt, Noah

AU - Ahrens, Martin

AU - Pieper, Mario

AU - Schönherr, Robert

AU - Jeschke, Lucie

AU - König, Peter

AU - Lampe, Marko

AU - Hüttmann, Gereon

PY - 2025

Y1 - 2025

N2 - We investigated the dynamic optical coherence tomography (dOCT) signal origins by correlative measurements together with spinning disk confocal microscopy (SDM). Furthermore, we propose dynamic contrasting for detecting organelle movement signatures in the sub-second range.

AB - We investigated the dynamic optical coherence tomography (dOCT) signal origins by correlative measurements together with spinning disk confocal microscopy (SDM). Furthermore, we propose dynamic contrasting for detecting organelle movement signatures in the sub-second range.

U2 - 10.1364/ECBO.2025.S4B.1

DO - 10.1364/ECBO.2025.S4B.1

M3 - Conference contribution

SP - S4B.1

BT - European Conferences on Biomedical Optics 2025

PB - Optica Publishing Group

ER -

Investigating dOCT signal origins and bringing a new contrast to fluorescence imaging

Abstract

UN SDGs

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