Abstract
Sensing of environmental parameters is critically important for cells of metazoan organisms. Members of the superfamily of bHLH‐PAS transcription factors, involved in oxygen sensing and circadian rhythm generation, are important players in such molecular pathways. The interplay between both networks includes a so far unknown factor, connecting PER2 (circadian clocks) to hypoxia sensing (HIF‐1 α) to result in a more adapted state of homeostasis at the right time.
| Original language | English |
|---|---|
| Journal | FEBS Journal |
| Volume | 284 |
| Issue number | 22 |
| Pages (from-to) | 3801-3803 |
| Number of pages | 3 |
| ISSN | 1742-464X |
| DOIs |
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| Publication status | Published - 01.11.2017 |
Funding
The research of author RD′s group is supported by the German Research Foundation (DFG) (KO5512/2-1). HO is supported by the DFG (GRK-1957 and SFB-134) and the Volkswagen Foundation.
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being -
SDG 8 Decent Work and Economic Growth -
SDG 10 Reduced Inequalities
Research Areas and Centers
- Academic Focus: Center for Brain, Behavior and Metabolism (CBBM)
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