Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI)

Astrid Brendemühl; Stefan Ostrowitzki; Uwe Altenburger; J. Christoph Haller; Jürgen Ruhlmann; Thorsten M. Buzug

doi:10.1007/978-3-540-68764-1_34

Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI)

Astrid Brendemühl, Stefan Ostrowitzki, Uwe Altenburger, J. Christoph Haller, Jürgen Ruhlmann, Thorsten M. Buzug

Institute of Medical Engineering

Abstract

Radiation therapy is an important method of treating neoplastic diseases with ionizing radiation. For this treatment electromagnetic or corpuscular (electrons, protons, neutrons) radiation is used which causes ionization and excitation in the energy absorbing tissue [1]. The conventional radiation therapy applies beams with a homogeneous dose distribution or uses wedges to optimize the dose to the cancerous volume and prevents high doses in organs of risk (e.g. rectum, eye). The individual treatment plan is developed by the physicist who sets the beams in a treatment planning system which calculates the dose distribution. With the objective of ideal adjustment to the cancerous volume it is advantageous to use the ``inverse treatment planning'' and the intensity-modulated radiation therapy (IMRT) especially for concave volumes. Therefore, the dose distribution is designated by the physicist and the individual treatment plan is developed including the number and direction of beams and the multi-leaf collimators' position. Due to the fact that the leaf collimator conforms the dose to the tumor volume IMRT protects the adjacent tissue as good as possible. Before an application of IMRT starts a quality assurance is important. It is especially necessary to check the accuracy of the system including the data of the planning software.

Original language	English
Title of host publication	Advances in Medical Engineering
Editors	Thorsten M. Buzug, Dietrich Holz, Jens Bongartz, Matthias Kohl-Bareis, Ulrich Hartmann, Simone Weber
Number of pages	6
Volume	114
Place of Publication	Berlin, Heidelberg
Publisher	Springer Berlin Heidelberg
Publication date	01.01.2007
Pages	205-210
ISBN (Print)	978-3-540-68763-4
ISBN (Electronic)	978-3-540-68764-1
DOIs	https://doi.org/10.1007/978-3-540-68764-1_34
Publication status	Published - 01.01.2007

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10.1007/978-3-540-68764-1_34

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Brendemühl, A., Ostrowitzki, S., Altenburger, U., Haller, J. C., Ruhlmann, J., & Buzug, T. M. (2007). Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI). In T. M. Buzug, D. Holz, J. Bongartz, M. Kohl-Bareis, U. Hartmann, & S. Weber (Eds.), Advances in Medical Engineering (Vol. 114, pp. 205-210). (Springer Proceedings in Physics; Vol. 114, No. 1). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-540-68764-1_34

Brendemühl, Astrid ; Ostrowitzki, Stefan ; Altenburger, Uwe et al. / Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI). Advances in Medical Engineering. editor / Thorsten M. Buzug ; Dietrich Holz ; Jens Bongartz ; Matthias Kohl-Bareis ; Ulrich Hartmann ; Simone Weber. Vol. 114 Berlin, Heidelberg : Springer Berlin Heidelberg, 2007. pp. 205-210 (Springer Proceedings in Physics; 1).

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title = "Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI)",

abstract = "Radiation therapy is an important method of treating neoplastic diseases with ionizing radiation. For this treatment electromagnetic or corpuscular (electrons, protons, neutrons) radiation is used which causes ionization and excitation in the energy absorbing tissue [1]. The conventional radiation therapy applies beams with a homogeneous dose distribution or uses wedges to optimize the dose to the cancerous volume and prevents high doses in organs of risk (e.g. rectum, eye). The individual treatment plan is developed by the physicist who sets the beams in a treatment planning system which calculates the dose distribution. With the objective of ideal adjustment to the cancerous volume it is advantageous to use the ``inverse treatment planning'' and the intensity-modulated radiation therapy (IMRT) especially for concave volumes. Therefore, the dose distribution is designated by the physicist and the individual treatment plan is developed including the number and direction of beams and the multi-leaf collimators' position. Due to the fact that the leaf collimator conforms the dose to the tumor volume IMRT protects the adjacent tissue as good as possible. Before an application of IMRT starts a quality assurance is important. It is especially necessary to check the accuracy of the system including the data of the planning software.",

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Brendemühl, A, Ostrowitzki, S, Altenburger, U, Haller, JC, Ruhlmann, J & Buzug, TM 2007, Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI). in TM Buzug, D Holz, J Bongartz, M Kohl-Bareis, U Hartmann & S Weber (eds), Advances in Medical Engineering. vol. 114, Springer Proceedings in Physics, no. 1, vol. 114, Springer Berlin Heidelberg, Berlin, Heidelberg, pp. 205-210. https://doi.org/10.1007/978-3-540-68764-1_34

Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI). / Brendemühl, Astrid; Ostrowitzki, Stefan; Altenburger, Uwe et al.
Advances in Medical Engineering. ed. / Thorsten M. Buzug; Dietrich Holz; Jens Bongartz; Matthias Kohl-Bareis; Ulrich Hartmann; Simone Weber. Vol. 114 Berlin, Heidelberg: Springer Berlin Heidelberg, 2007. p. 205-210 (Springer Proceedings in Physics; Vol. 114, No. 1).

Research output: Chapters in Books/Reports/Conference Proceedings › Conference contribution › peer-review

TY - GEN

T1 - Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI)

AU - Brendemühl, Astrid

AU - Ostrowitzki, Stefan

AU - Altenburger, Uwe

AU - Haller, J. Christoph

AU - Ruhlmann, Jürgen

AU - Buzug, Thorsten M.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Radiation therapy is an important method of treating neoplastic diseases with ionizing radiation. For this treatment electromagnetic or corpuscular (electrons, protons, neutrons) radiation is used which causes ionization and excitation in the energy absorbing tissue [1]. The conventional radiation therapy applies beams with a homogeneous dose distribution or uses wedges to optimize the dose to the cancerous volume and prevents high doses in organs of risk (e.g. rectum, eye). The individual treatment plan is developed by the physicist who sets the beams in a treatment planning system which calculates the dose distribution. With the objective of ideal adjustment to the cancerous volume it is advantageous to use the ``inverse treatment planning'' and the intensity-modulated radiation therapy (IMRT) especially for concave volumes. Therefore, the dose distribution is designated by the physicist and the individual treatment plan is developed including the number and direction of beams and the multi-leaf collimators' position. Due to the fact that the leaf collimator conforms the dose to the tumor volume IMRT protects the adjacent tissue as good as possible. Before an application of IMRT starts a quality assurance is important. It is especially necessary to check the accuracy of the system including the data of the planning software.

AB - Radiation therapy is an important method of treating neoplastic diseases with ionizing radiation. For this treatment electromagnetic or corpuscular (electrons, protons, neutrons) radiation is used which causes ionization and excitation in the energy absorbing tissue [1]. The conventional radiation therapy applies beams with a homogeneous dose distribution or uses wedges to optimize the dose to the cancerous volume and prevents high doses in organs of risk (e.g. rectum, eye). The individual treatment plan is developed by the physicist who sets the beams in a treatment planning system which calculates the dose distribution. With the objective of ideal adjustment to the cancerous volume it is advantageous to use the ``inverse treatment planning'' and the intensity-modulated radiation therapy (IMRT) especially for concave volumes. Therefore, the dose distribution is designated by the physicist and the individual treatment plan is developed including the number and direction of beams and the multi-leaf collimators' position. Due to the fact that the leaf collimator conforms the dose to the tumor volume IMRT protects the adjacent tissue as good as possible. Before an application of IMRT starts a quality assurance is important. It is especially necessary to check the accuracy of the system including the data of the planning software.

UR - https://www.researchgate.net/publication/226395172_Intensity-Modulated_Radiation_Therapy_-_Quality_Assurance_with_the_Mutual_Information_Index_MI

U2 - 10.1007/978-3-540-68764-1_34

DO - 10.1007/978-3-540-68764-1_34

M3 - Conference contribution

SN - 978-3-540-68763-4

VL - 114

T3 - Springer Proceedings in Physics

SP - 205

EP - 210

BT - Advances in Medical Engineering

A2 - Buzug, Thorsten M.

A2 - Holz, Dietrich

A2 - Bongartz, Jens

A2 - Kohl-Bareis, Matthias

A2 - Hartmann, Ulrich

A2 - Weber, Simone

PB - Springer Berlin Heidelberg

CY - Berlin, Heidelberg

ER -

Brendemühl A, Ostrowitzki S, Altenburger U, Haller JC, Ruhlmann J, Buzug TM. Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI). In Buzug TM, Holz D, Bongartz J, Kohl-Bareis M, Hartmann U, Weber S, editors, Advances in Medical Engineering. Vol. 114. Berlin, Heidelberg: Springer Berlin Heidelberg. 2007. p. 205-210. (Springer Proceedings in Physics; 1). doi: 10.1007/978-3-540-68764-1_34

Intensity-Modulated Radiation Therapy: Quality Assurance with the Mutual Information Index (MI)

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