Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Coralie Vacher, Zdenek Berger, Janet E. Davies, Shouqing Luo, Lourdes G. Oroz, Francesco Scaravilli, Douglas F. Easton, Rainer Duden, Cahir J. O'Kane, David C. Rubinsztein*

*Corresponding author for this work
1789 Citations (Scopus)

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Pharmacology, Toxicology and Pharmaceutical Science

Neuroscience