TY - JOUR
T1 - Influence of System Matrix Concentration and Frequency Selection on Reconstructed MPI Signals
AU - Jegatheeswaran, Sathurya
AU - Meenen, Hanna
AU - Buzug, Thorsten M.
AU - Gräfe, Ksenija
N1 - Publisher Copyright:
© 2026 Jegatheeswaran et al.
PY - 2026
Y1 - 2026
N2 - In Magnetic Particle Imaging (MPI), the system matrix (SM) characterizes the spatial encoding properties of the imaging system and the magnetic nanoparticle response. Ideally, for linear particle magnetization behavior, the concentration at which the SM is measured should not affect the reconstructed image. In this study, two SMs recorded with tracer concentrations of 8.5 mg(Fe)/ml and 1.92 mg(Fe)/ml were investigated. We show that, although the same SM is used, reconstruction discrepancies occur when the frequency coverage differs. We therefore propose to determine the usable frequency components based on the lower concentration SM to ensure a consistent reconstruction basis.
AB - In Magnetic Particle Imaging (MPI), the system matrix (SM) characterizes the spatial encoding properties of the imaging system and the magnetic nanoparticle response. Ideally, for linear particle magnetization behavior, the concentration at which the SM is measured should not affect the reconstructed image. In this study, two SMs recorded with tracer concentrations of 8.5 mg(Fe)/ml and 1.92 mg(Fe)/ml were investigated. We show that, although the same SM is used, reconstruction discrepancies occur when the frequency coverage differs. We therefore propose to determine the usable frequency components based on the lower concentration SM to ensure a consistent reconstruction basis.
UR - https://www.scopus.com/pages/publications/105034449046
U2 - 10.18416/IJMPI.2026.2603026
DO - 10.18416/IJMPI.2026.2603026
M3 - Journal articles
AN - SCOPUS:105034449046
SN - 2365-9033
VL - 12
JO - International Journal on Magnetic Particle Imaging
JF - International Journal on Magnetic Particle Imaging
IS - 1
M1 - 2603026
ER -