Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases

G. Brinkmann; U. H. Melchert; C. Muhle; J. Brossmann; J. Link; M. Reuter; M. Heller

doi:10.1007/BF00619955

Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases

G. Brinkmann^*, U. H. Melchert, C. Muhle, J. Brossmann, J. Link, M. Reuter, M. Heller

^*Corresponding author for this work

Institute of Neuroradiology

University of Kiel

7 Citations (Scopus)

Abstract

The purpose of this study was to determine the influence of different fasting periods on the in vivo P-31-MR spectroscopy of the healthy liver and patients with liver metastases. Image-guided localized P-31-MRS was performed in 24 patients with liver metastases and in 20 healthy volunteers. The spectra were obtained with a whole body scanner operating at 1.5 T using a surface coil. The P-31-MRS was performed after a fasting period of 3-5 h (group 1) and after overnight fasting (group 2). The PME/β-NTP, PDE/β-NTP and Pi/β-NTP were calculated from P-31-MR spectra and were compared in relation to the nutrition status of the volunteers and patients. The PME/β-NTP and PDE/β-NTP were significantly increased in spectra of patients with metastases. There were no significant changes in the ratios of phosphorus metabolites in healthy liver tissue or in liver metastases after a fasting period of 3-5 h as compared with overnight fasting.

Original language	English
Journal	European Radiology
Volume	6
Issue number	1
Pages (from-to)	62-65
Number of pages	4
ISSN	0938-7994
DOIs	https://doi.org/10.1007/BF00619955
Publication status	Published - 01.01.1996

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title = "Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases",

abstract = "The purpose of this study was to determine the influence of different fasting periods on the in vivo P-31-MR spectroscopy of the healthy liver and patients with liver metastases. Image-guided localized P-31-MRS was performed in 24 patients with liver metastases and in 20 healthy volunteers. The spectra were obtained with a whole body scanner operating at 1.5 T using a surface coil. The P-31-MRS was performed after a fasting period of 3-5 h (group 1) and after overnight fasting (group 2). The PME/β-NTP, PDE/β-NTP and Pi/β-NTP were calculated from P-31-MR spectra and were compared in relation to the nutrition status of the volunteers and patients. The PME/β-NTP and PDE/β-NTP were significantly increased in spectra of patients with metastases. There were no significant changes in the ratios of phosphorus metabolites in healthy liver tissue or in liver metastases after a fasting period of 3-5 h as compared with overnight fasting.",

author = "G. Brinkmann and Melchert, {U. H.} and C. Muhle and J. Brossmann and J. Link and M. Reuter and M. Heller",

year = "1996",

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doi = "10.1007/BF00619955",

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T1 - Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases

AU - Brinkmann, G.

AU - Melchert, U. H.

AU - Muhle, C.

AU - Brossmann, J.

AU - Link, J.

AU - Reuter, M.

AU - Heller, M.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - The purpose of this study was to determine the influence of different fasting periods on the in vivo P-31-MR spectroscopy of the healthy liver and patients with liver metastases. Image-guided localized P-31-MRS was performed in 24 patients with liver metastases and in 20 healthy volunteers. The spectra were obtained with a whole body scanner operating at 1.5 T using a surface coil. The P-31-MRS was performed after a fasting period of 3-5 h (group 1) and after overnight fasting (group 2). The PME/β-NTP, PDE/β-NTP and Pi/β-NTP were calculated from P-31-MR spectra and were compared in relation to the nutrition status of the volunteers and patients. The PME/β-NTP and PDE/β-NTP were significantly increased in spectra of patients with metastases. There were no significant changes in the ratios of phosphorus metabolites in healthy liver tissue or in liver metastases after a fasting period of 3-5 h as compared with overnight fasting.

AB - The purpose of this study was to determine the influence of different fasting periods on the in vivo P-31-MR spectroscopy of the healthy liver and patients with liver metastases. Image-guided localized P-31-MRS was performed in 24 patients with liver metastases and in 20 healthy volunteers. The spectra were obtained with a whole body scanner operating at 1.5 T using a surface coil. The P-31-MRS was performed after a fasting period of 3-5 h (group 1) and after overnight fasting (group 2). The PME/β-NTP, PDE/β-NTP and Pi/β-NTP were calculated from P-31-MR spectra and were compared in relation to the nutrition status of the volunteers and patients. The PME/β-NTP and PDE/β-NTP were significantly increased in spectra of patients with metastases. There were no significant changes in the ratios of phosphorus metabolites in healthy liver tissue or in liver metastases after a fasting period of 3-5 h as compared with overnight fasting.

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DO - 10.1007/BF00619955

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AN - SCOPUS:0029688256

SN - 0938-7994

VL - 6

SP - 62

EP - 65

JO - European Radiology

JF - European Radiology

IS - 1

ER -

Influence of different fasting periods on P-31-MR-spectroscopy of the liver in normals and patients with liver metastases

Abstract

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