In-vivo retinal imaging with off-axis full-field time-domain optical coherence tomography

Helge Sudkamp*, Peter Koch, Hendrik Spahr, Dierck Hillmann, Gesa Franke, Michael M�nst, Fred Reinholz, Reginald Birngruber, Gereon H�ttmann

*Corresponding author for this work
3 Citations (Scopus)


With a simple setup, mainly composed of a low coherence light source and a camera, full-field optical coherence tomography (FF-OCT) allows volumetric tissue imaging. However, fringe washout constrains its use in retinal imaging. Here, we present a novel motion-insensitive approach to FF-OCT, which introduces path-length differences between the reference and the sample light in neighboring pixels using an off-axis reference beam. The temporal carrier frequency in scanned time-domain OCT is replaced by a spatial carrier frequency. Volumetric in-vivo FF-OCT measurements of the human retina were acquired in only 1.3 s, comparable to the acquisition times of current clinically used OCT devices.

Original languageEnglish
JournalOptics Letters
Issue number21
Pages (from-to)4987-4990
Number of pages4
Publication statusPublished - 01.11.2016


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