Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic 31PMR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive 31P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.
|Translated title of the contribution||In-vivo 31P-MR spectroscopy of the calf muscles in arterial occlusive disease|
|Journal||RoFo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Neuen Bildgebenden Verfahren|
|Number of pages||7|
|Publication status||Published - 01.01.1992|