IN-VIVO-(31)PHOSPHOR-MR-SPEKTROSKOPIE DER WADENMUSKULATUR BEI ARTERIELLER VERSCHLUSSKRANKHEIT

U. H. Melchert; G. Brinkmann; K. Forger; M. Gleim; F. Wunsch-Binder; C. Maier; G. Zick

IN-VIVO-(31)PHOSPHOR-MR-SPEKTROSKOPIE DER WADENMUSKULATUR BEI ARTERIELLER VERSCHLUSSKRANKHEIT

Translated title of the contribution: In-vivo ³¹P-MR spectroscopy of the calf muscles in arterial occlusive disease

U. H. Melchert^*, G. Brinkmann, K. Forger, M. Gleim, F. Wunsch-Binder, C. Maier, G. Zick

^*Corresponding author for this work

Institute of Neuroradiology

University of Kiel

5 Citations (Scopus)

Abstract

Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic ³¹PMR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive ³¹P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.

Translated title of the contribution	In-vivo ³¹P-MR spectroscopy of the calf muscles in arterial occlusive disease
Original language	German
Journal	RoFo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Neuen Bildgebenden Verfahren
Volume	156
Issue number	4
Pages (from-to)	346-352
Number of pages	7
ISSN	0936-6652
Publication status	Published - 01.01.1992

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title = "IN-VIVO-(31)PHOSPHOR-MR-SPEKTROSKOPIE DER WADENMUSKULATUR BEI ARTERIELLER VERSCHLUSSKRANKHEIT",

abstract = "Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic 31PMR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive 31P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.",

author = "Melchert, {U. H.} and G. Brinkmann and K. Forger and M. Gleim and F. Wunsch-Binder and C. Maier and G. Zick",

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language = "Deutsch",

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T1 - IN-VIVO-(31)PHOSPHOR-MR-SPEKTROSKOPIE DER WADENMUSKULATUR BEI ARTERIELLER VERSCHLUSSKRANKHEIT

AU - Melchert, U. H.

AU - Brinkmann, G.

AU - Forger, K.

AU - Gleim, M.

AU - Wunsch-Binder, F.

AU - Maier, C.

AU - Zick, G.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic 31PMR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive 31P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.

AB - Muscle metabolism was measured in 7 patients with arterial occlusive disease and symptoms of intermittent claudication both before and after percutaneous vascular neurolysis by means of dynamic 31PMR spectroscopy. Phosphorus spectra of the involved calf muscles were determined before, during and after defined treadmill exercise. In addition to pH values the phosphocreatine content was measured during activity and recovery phases. There was close correlation in these patients between the increase in claudication distance and more rapid regeneration of phosphocreatine following neurolysis. However, none of the patients achieved normal values of phosphate metabolism. By means of the non-invasive 31P-MR spectroscopy it was possible for the first time to demonstrate the biochemical changes associated with neurolytic lumbar sympathetic blockade.

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M3 - Zeitschriftenaufsätze

C2 - 1571516

AN - SCOPUS:0026611645

SN - 0936-6652

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SP - 346

EP - 352

JO - RoFo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Neuen Bildgebenden Verfahren

JF - RoFo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Neuen Bildgebenden Verfahren

IS - 4

ER -

IN-VIVO-(31)PHOSPHOR-MR-SPEKTROSKOPIE DER WADENMUSKULATUR BEI ARTERIELLER VERSCHLUSSKRANKHEIT

Abstract

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