IN-VITRO-UNTERSUCHUNGEN ZUR GEPULSTEN LASERANGIOPLASTIE IN FLUSSIGEM UND GASFORMIGEM MEDIUM

Translated title of the contribution: In vitro studies on pulsed laser angioplasty in liquid and gaseous medium

M. Zwaan*, U. Behnle, R. Engelhardt, A. Vogel, W. Kloess, R. Birngruber, H. D. Weiss

*Corresponding author for this work

Abstract

Purpose: In a vascular model the mechanisms of a pulsed dye laser working in a liquid and a gaseous environment was tested and documented by means of a high-speed camera. Methods: The pulse application (630 nm wavelength) on a target of calcified arterial plaque material was detected at intervals of 20 μs up to 800 μs total time. Results: In water the laser beam created a cavitation bubble which expanded from 0 to 450 μs from a radius 0 to 3 mm and collapsed afterwards. The average expansion velocity of the bubble was 80 m/s in the first 20 μs and the resulting velocity of the tube model wall was 10 m/s. Compared with gaseous atmosphere there was no bubble and consecutively no wall stress. Conclusion: It is obvious that laser angioplasty causes wall stress and destruction of different vascular layers. This might be the initial stimulation for restenosis. In gaseous atmosphere laser angioplasty should be more protective.

Translated title of the contributionIn vitro studies on pulsed laser angioplasty in liquid and gaseous medium
Original languageGerman
JournalRoFo Fortschritte auf dem Gebiete der Rontgenstrahlen und der Neuen Bildgebenden Verfahren
Volume164
Issue number1
Pages (from-to)68-71
Number of pages4
ISSN0936-6652
Publication statusPublished - 01.1996

Research Areas and Centers

  • Academic Focus: Biomedical Engineering

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