In silico fine-mapping: Narrowing disease-associated loci by intergenomics

Pablo Serrano-Fernández*, Saleh M. Ibrahim, Dirk Koczan, Uwe K. Zettl, Steffen Möller

*Corresponding author for this work
2 Citations (Scopus)


Summary: Genetic linkage and association studies define quantitative trait loci (QTLs) and susceptibility loci (SLs) that influence the phenotype of polygenic traits. A web-accessible application was created to identify intergenomic consensuses to fine map QTLs and SLs in silico and select particularly promising candidate genes for such traits. Furthermore, this approach offers an empirical evaluation of animal models for their applicability to the study of human traits.

Original languageEnglish
Issue number8
Pages (from-to)1737-1738
Number of pages2
Publication statusPublished - 15.04.2005


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