TY - CONF
T1 - Improved Estimation of the Magnetic Nanoparticle Diameter with a Magnetic Particle Spectrometer and Combined Fields
AU - Biederer, S.
AU - Knopp, T.
AU - Sattel, T. F.
AU - Erbe, M.
AU - Buzug, T. M.
PY - 2010
Y1 - 2010
N2 - Introduction: In the tomographic imaging technique magnetic particle imaging (MPI), the spatial distribution of super-paramagnetic iron-oxide nanoparticles (SPIOs) can be visualized in real-time [1, 2, 3, 4]. MPI takes advantage of the nonlinear magnetization behavior of the SPIOs. In simulations it has been shown [5, 6] that the iron-core diameter has a high impact on the received signal and, thus, also on the imaging quality. For prediction of the imaging quality or for a model-based reconstruction [7], the knowledge of the exact ironcore size distribution is indispensable. However, an estimation of the iron-core size e.g. by transmission electron microscopy is complicated and time consuming. A magnetic particle spectrometer (MPS) exploits the same physical effect as used in MPI. Based on MPS measurements, a new method to estimate the iron-core size distribution was proposed [8]. In this contribution an improvement of this estimation method is presented by using combined excitation fields.
AB - Introduction: In the tomographic imaging technique magnetic particle imaging (MPI), the spatial distribution of super-paramagnetic iron-oxide nanoparticles (SPIOs) can be visualized in real-time [1, 2, 3, 4]. MPI takes advantage of the nonlinear magnetization behavior of the SPIOs. In simulations it has been shown [5, 6] that the iron-core diameter has a high impact on the received signal and, thus, also on the imaging quality. For prediction of the imaging quality or for a model-based reconstruction [7], the knowledge of the exact ironcore size distribution is indispensable. However, an estimation of the iron-core size e.g. by transmission electron microscopy is complicated and time consuming. A magnetic particle spectrometer (MPS) exploits the same physical effect as used in MPI. Based on MPS measurements, a new method to estimate the iron-core size distribution was proposed [8]. In this contribution an improvement of this estimation method is presented by using combined excitation fields.
M3 - Conference Papers
SP - 954
ER -