Immunopathology of ANCA-Associated Vasculitis

Csernok Elena, Müller Antje, Wolfgang L. Gross*

*Corresponding author for this work
45 Citations (Scopus)


During the past few years remarkable progress has been achieved in the understanding of the pathogenic mechanisms leading to vascular inflammation and injury in ANCA-associated vasulitides (AAV): Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and Churg Strauss syndrome (CSS). In this paper we review the immunopathology of these diseases by describing the role of autoantibodies (ANCA), dysregulation and abnormalities at the cellular level, genetic background and environmental factors that predispose to autoimmune response.

Original languageEnglish
JournalInternal Medicine
Issue number10
Pages (from-to)759-765
Number of pages7
Publication statusPublished - 10.1999

Research Areas and Centers

  • Academic Focus: Center for Infection and Inflammation Research (ZIEL)


Dive into the research topics of 'Immunopathology of ANCA-Associated Vasculitis'. Together they form a unique fingerprint.

Cite this