Immunohistochemical visualization of the enteric nervous system using antibodies against Protein gene product (PGP) 9.5

Heinz Jürgen Krammer; Süleyman Tuna Karahan; Elisabeth Rumpel; Matthias Klinger; Wolfgang Kühnel

doi:10.1016/S0940-9602(11)80029-4

Immunohistochemical visualization of the enteric nervous system using antibodies against Protein gene product (PGP) 9.5

Heinz Jürgen Krammer^*, Süleyman Tuna Karahan, Elisabeth Rumpel, Matthias Klinger, Wolfgang Kühnel

^*Corresponding author for this work

Institute of Anatomy

67 Citations (Scopus)

Abstract

Both the investigation of the enteric nervous system and the diagnosis of its pathological changes require reliable staining methods. In order to assess the potential of protein gene product (PGP) 9.5 as a marker for the enteric nervous system, we examined its immunoreaction in whole-mount preparations of the guinea pig and porcine small intestine, using a rabbit polyclonal antiserum.The immunohistochemical technique reveals the fundamental architectural features of the ganglionic and aganglionic plexuses. Furthermore, it enables a reproducible and differentiated visualization of the enteric nerve cells to be made, so that the various nerve cell types can be morphologically identified.

Original language	English
Journal	Annals of Anatomy
Volume	175
Issue number	4
Pages (from-to)	321-325
Number of pages	5
ISSN	0940-9602
DOIs	https://doi.org/10.1016/S0940-9602(11)80029-4
Publication status	Published - 1993

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Academic Focus: Center for Infection and Inflammation Research (ZIEL)

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10.1016/S0940-9602(11)80029-4

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abstract = "Both the investigation of the enteric nervous system and the diagnosis of its pathological changes require reliable staining methods. In order to assess the potential of protein gene product (PGP) 9.5 as a marker for the enteric nervous system, we examined its immunoreaction in whole-mount preparations of the guinea pig and porcine small intestine, using a rabbit polyclonal antiserum.The immunohistochemical technique reveals the fundamental architectural features of the ganglionic and aganglionic plexuses. Furthermore, it enables a reproducible and differentiated visualization of the enteric nerve cells to be made, so that the various nerve cell types can be morphologically identified.",

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AU - Krammer, Heinz Jürgen

AU - Karahan, Süleyman Tuna

AU - Rumpel, Elisabeth

AU - Klinger, Matthias

AU - Kühnel, Wolfgang

PY - 1993

Y1 - 1993

N2 - Both the investigation of the enteric nervous system and the diagnosis of its pathological changes require reliable staining methods. In order to assess the potential of protein gene product (PGP) 9.5 as a marker for the enteric nervous system, we examined its immunoreaction in whole-mount preparations of the guinea pig and porcine small intestine, using a rabbit polyclonal antiserum.The immunohistochemical technique reveals the fundamental architectural features of the ganglionic and aganglionic plexuses. Furthermore, it enables a reproducible and differentiated visualization of the enteric nerve cells to be made, so that the various nerve cell types can be morphologically identified.

AB - Both the investigation of the enteric nervous system and the diagnosis of its pathological changes require reliable staining methods. In order to assess the potential of protein gene product (PGP) 9.5 as a marker for the enteric nervous system, we examined its immunoreaction in whole-mount preparations of the guinea pig and porcine small intestine, using a rabbit polyclonal antiserum.The immunohistochemical technique reveals the fundamental architectural features of the ganglionic and aganglionic plexuses. Furthermore, it enables a reproducible and differentiated visualization of the enteric nerve cells to be made, so that the various nerve cell types can be morphologically identified.

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M3 - Journal articles

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AN - SCOPUS:0027284044

SN - 0940-9602

VL - 175

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JO - Annals of Anatomy

JF - Annals of Anatomy

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ER -

Immunohistochemical visualization of the enteric nervous system using antibodies against Protein gene product (PGP) 9.5

Abstract

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