Immunohistochemical detection of hemoglobin in frost erythema

E. E. Türk*, J. P. Sperhake, B. Madea, J. Preuß, M. Tsokos

*Corresponding author for this work
11 Citations (Scopus)


Reddish discoloration of exposed skin areas, called frost erythema, is an important criterion for the diagnosis of fatal hypothermia. In the present study, we used immunohistochemistry in a prospective trial to show that on the molecular level, the correlate of frost erythema is hemoglobin without hemorrhage. Furthermore, we compared routine histological and immunohistochemical features of frost erythema, hematoma and livor mortis and established some criteria for their histological differentiation.

Original languageEnglish
JournalForensic Science International
Issue number2-3
Pages (from-to)131-134
Number of pages4
Publication statusPublished - 10.05.2006


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