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Imatinib and leptomycin B are effective in overcoming imatinib-resistance due to Bcr-Abl amplification and clonal evolution but not due to Bcr-Abl kinase domain mutation

Rama Krishna Kancha, Nikolas Von Bubnoff, Cornelius Miething, Christian Peschel, Katharina S. Götze, Justus Duyster*

*Corresponding author for this work

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