Imaging-based outcome prediction in patients with intracerebral hemorrhage

Peter B. Sporns*, André Kemmling, Jens Minnerup, Uta Hanning, Walter Heindel

*Corresponding author for this work
1 Citation (Scopus)


Besides the established spot sign in computed tomography angiography (CTA), recently investigated imaging predictors of hematoma growth in noncontrast computed tomography (NCCT) suggest great potential for outcome prediction in patients with intracerebral hemorrhage (ICH). Secondary hematoma growth is an appealing target for therapeutic interventions because in contrast to other determined factors, it is potentially modifiable. Even more initial therapy studies failed to demonstrate clear therapeutic benefits, there is a need for an effective patient selection using imaging markers to identify patients at risk for poor outcome and thereby tailor individual treatments for every patient. Hence, this review gives an overview about the current literature on NCCT imaging markers for neurological outcome prediction and aims to clarify the association with the established spot sign. Moreover, it demonstrates the clinical impact of these parameters and gives a roadmap for future imaging research in patients with intracerebral hemorrhage.

Original languageEnglish
JournalActa Neurochirurgica
Issue number8
Pages (from-to)1663-1670
Number of pages8
Publication statusPublished - 01.08.2018

DFG Research Classification Scheme

  • 206-07 Clinical Neurology Neurosurgery and Neuroradiology


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