Imaging and analysis of angiogenesis for skin transplantation by microangiography

A. P. Condurache, T. Aach, S. Grzybowski, H. G. Machens

Abstract

The success of skin transplantations depends on a proper revascularization of the transplanted tissue. Angiogenesis (vessel growth) in the transplanted dermal matrices can be stimulated by administering different drugs. To evaluate the effectiveness of different drug treatments in an experimental setting using laboratory animals, vessels in transplant samples are visualized by so-called micro-angiograms, i.e., X-ray images after contrast agent injection. We describe a framework for the acquisition of such micro-angiograms as well as for the subsequent semi-automatic analysis of angiogenesis. Central to our analysis is the segmentation of small fasciocutaneous vessels in the transplant sample.

Original languageEnglish
Title of host publication IEEE International Conference on Image Processing 2005
Number of pages4
PublisherIEEE
Publication date01.12.2005
Pages1250-1253
Article number1530289
ISBN (Print)0-7803-9134-9
DOIs
Publication statusPublished - 01.12.2005
EventIEEE International Conference on Image Processing 2005 - Genova, Italy
Duration: 11.09.200514.09.2005
Conference number: 68264

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